The Optimization of Porous Materials for Immobilized Enzyme (IME) Systems
Critical parameters involved in the selection of support materials in the immobilization of biologically active materials are discussed. The importance of physical properties such as pore morphology, surface area and particle size relative to the final activity of the enzyme is shown using glucoamylase IME as a model system. The process of selection of specific materials with respect to the environmental conditions of the enzyme and the chemical durability of the support is considered, as are the mechanical properties required in the scale up of an application.
KeywordsPorous Material Immobilize Enzyme Carrier Material Pore Morphology Chemical Durability
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