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Separation and Characterization of Myelin Proteins

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 32)

Abstract

Within the group of plasma membranes, isolated and studied until now, the myelin membrane has a typical characteristically low protein content of 20 percent (3,15,18) and a protein composition of reduced complexity. By work on isolated cerebral myelin, the encephalitogenic basic protein was directly shown to be a myelin protein (17, 18). Autilio (2) applied gel filtration in chloroformmethanol and obtained a further myelin protein fraction comprising 55 to 65 percent of total myelin proteins. This protein fraction had an amino acid composition almost identical to the classical Folch-Lees proteolipid protein (13) which was extracted from cerebral white matter and subjected to a purification step.

Keywords

Myelin Basic Protein Basic Protein Myelin Protein Cerebral White Matter Proteolipid Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1972

Authors and Affiliations

  • E. Mehl
    • 1
  1. 1.Division of NeurochemistryMax-Planck-Institut of PsychiatryMunichGermany

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