Studies on the Transfer of Subviral Infectivity from SV40-Induced Hamster Tumor Cells to Indicator Cells
Some of the factors involved in the interaction between SV40-induced, virogenic hamster tumor cells and indicator cells were investigated. The number of detectable virogenic tumor cells was found to depend on their plating efficiency. Demonstration of virogenicity required viability of the tumor cells as well as direct contact with the indicator cells. This interaction could be enhanced by the presence of ultraviolet-irradiated Sendai virus. The tumor cells retained their virogenic character following prolonged passage in the presence of 10μg/ml of cytosine arabinoside.
KeywordsMixed Culture Infectious Virus Cytosine Arabinoside Indicator Cell Sendai Virus
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