Antihypertensive Agents: Mechanisms of Drug Action

  • Bernard Waeber
  • Hans R. Brunner
Part of the Atlas of Heart Diseases book series (AD)


Hypertension is a major risk factor for the development of cardiovascular diseases. There is a direct relationship between blood pressure and the incidence of stroke and coronary events [1]. Even modest elevations in blood pressure (both systolic and diastolic) are associated with an increased health risk. Hypertension also predisposes to left ventricular hypertrophy and chronic renal failure [2, 3].


Vascular Smooth Muscle Cell Calcium Antagonist Total Peripheral Resistance Ethacrynic Acid Distal Convoluted Tubule 
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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Bernard Waeber
  • Hans R. Brunner

There are no affiliations available

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