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Heart Valve Replacement with the St. Jude Medical® Valve Prosthesis: Long-Term Experience in 743 Patients Receiving Valve Implants in Switzerland

  • D. Burckhardt
  • D. Striebel
  • S. Vogt
  • A. Hoffmann
  • J. Roth
  • U. Althaus
  • J. J. Goy
  • H. Sadeghi
  • E. Grädel

Abstract

From November 1978 to June 1986, 743 patients received 828 ST. JUDE MEDICAL® valves (SJM) at the University Clinics of Basel, Berne, and Lausanne, Switzerland. There were 445 men and 298 women, with a mean age of 57 years (range 1–83 years), who were followed for a mean of 2.6 years (22,768 patient-months). Aortic valve replacement (AVR) was performed in 456 patients, mitral valve replacement (MVR) in 200 patients, tricuspid valve replacement (TVR) in 6 patients, double valve replacement in 77 patients, and triple valve replacement in 4 patients. In 187 patients, additional surgical interventions were performed. Operative mortality for the entire population was 1.6% and the 4-week perioperative mortality was 4.0%. During the mean follow-up period of 2.6 years, an additional 58 patients died, accounting for an annual mortality rate of 3.1%. Eighteen of these patients died of noncardiac causes, leaving an annual cardiac mortality rate of 2.1%. The thromboembolic rate was 1.25% per patient-year after AVR, 3.0% per patient-year after MVR, and 1.1% per patient-year after MuVR. In 8 of 32 patients (25%) with thromboembolic complications, symptoms were irreversible and in 14 of 32 patients (44%), the prothrombin time was not within therapeutic range. The incidence of major bleeding complications was 1.3% per patient-year.

Keywords

Valve Replacement Hemolytic Anemia Aortic Valve Replacement Mitral Valve Replacement Thromboembolic Complication 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • D. Burckhardt
  • D. Striebel
  • S. Vogt
  • A. Hoffmann
  • J. Roth
  • U. Althaus
  • J. J. Goy
  • H. Sadeghi
  • E. Grädel

There are no affiliations available

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