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A Seven-Year Experience with the St. Jude Medical® Heart Valve

  • H. O’Kane
  • D. Gladstone
  • L. Hamilton
  • I. Galvin
  • I. Cleland

Abstract

From May 1979 to October 1986, 442 ST. JUDE MEDICAL® valves (175 aortic, 142 mitral, and 61 multiple valve replacements) were inserted in 378 patients, ages 5 to 82 years. The operative mortality rates (30-day) were 1.1% aortic, 4.2% mitral, and 8.2% multiple valve replacement; and the late mortality was 6.8% aortic, 6.3% mitral, and 1.6% multiple valve replacement. All patients were anticoagulated. Three hundred seventy-eight patients have been followed for a total of 912 patient-years. During that time we have not recorded a single occurrence of primary structural failure or significant hemolysis in any patient. One aortic valve patient stopped taking her anticoagulant and the valve thrombosed; it was successfully replaced. In another patient, the mitral valve thrombosed after she switched from warfarin to subcutaneous heparin when she became pregnant; this valve was also successfully replaced. Twenty-four patients experienced isolated thromboembolic episodes (13 major, 11 minor)—an incidence of 2.7% per patient-year (2.6% aortic, 2.8% mitral, and 2.3% multiple). Included in the group were 9 children aged 5 to 16 years, 7 with mitral valve implants and 2 with aortic valve implants. One 9-year-old child who had an aortic valve implant for acute bacterial endocarditis died 2 months postoperatively with multiple organ failure. The remaining 8 patients, all on anticoagulation, continue to make excellent progress, 1 to 6 years later.

Keywords

Aortic Valve Mitral Valve Valve Replacement Aortic Valve Replacement Prosthetic Valve 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Kluwer Academic Publishers 1989

Authors and Affiliations

  • H. O’Kane
  • D. Gladstone
  • L. Hamilton
  • I. Galvin
  • I. Cleland

There are no affiliations available

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