DRTF1/E2F: A Molecular Switch in Cell Cycle Control

  • Rowena Girling
  • Nicholas B. La Thangue
Part of the Progress in Gene Expression book series (PRGE)


The cell cycle is a series of phases through which a cell must pass in order to divide. It is usually considered to be composed of four phases: the gap before DNA replication (G1), the DNA synthesis phase (S), the gap after DNA replication (G2) and the mitotic phase (M). In fact these phases represent a series of complex events which are regulated at different levels. One important level of control is the regulation of the transcriptional activity of particular genes during the cell cycle.


Retinoblastoma Protein Pocket Protein Viral Oncoproteins Cellular Transcription Factor Pocket Region 
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© Birkhäuser Boston 1995

Authors and Affiliations

  • Rowena Girling
  • Nicholas B. La Thangue

There are no affiliations available

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