Promoters, Enhancers, and Inducible Elements for Gene Therapy

  • Robert G. Whalen


If the field of gene therapy of human diseases is in its infancy, attempts to modulate the expression of transferred genes is an endeavor which is still in gestation. The midwives to the birth of this area are those molecular biologists who are actively involved in the study of the control of gene expression. In particular, the tremendous surge of the last several years in understanding of the promoter elements and the protein factors involved in transcriptional regulation are beginning to find application to problems of gene therapy.


Gene Therapy Core Promoter Globin Gene cAMP Response Element Binding Duchenne Muscular Dystrophy 
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© Birkhäuser Boston 1994

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  • Robert G. Whalen

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