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Mapping the Mind onto the Brain

  • James Olds

Abstract

Models of the mind, and the hope that these could be tied to neuroanatomical structures by brain maps, have motivated much of my research.

Keywords

Conditioned Stimulus Brain Stimulation Auditory Cortex Cochlear Nucleus Rewarding Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Anand, B.K., and Brobeck, J.R. (1951): Hypothalamic control of food intake in rats and cats. Tale J. Biol. Med. 24:123–140.Google Scholar
  2. Crow, T. J. (1972): A map of the rat mesencephalon for electrical self-stimulation. Brain Res. 36:265–273.PubMedCrossRefGoogle Scholar
  3. Crow, T.J., Spear, P. J., and Arbuthnott, G. W. (1972): Intracranial self-stimulation with electrodes in the region of the locus coeruleus. Brain Res. 36:275–287.PubMedCrossRefGoogle Scholar
  4. Dafny, N., Bental, E., and Feldman, S. (1965): Effect of sensory stimuli on single unit activity in the posterior hypothalamus. Electroencephalogr. Clin. Neurophysiol. 19:256–263.PubMedCrossRefGoogle Scholar
  5. Deutsch, J. A. (1963): Learning and electrical self-stimulation of the brain. J. Theor. Biol. 4:193–214.PubMedCrossRefGoogle Scholar
  6. Dews, P. B. (1958): Studies on behavior. IV. Stimulant actions of methamphetamine. J. Pharmacol. Exp. Ther. 122:137–147.PubMedGoogle Scholar
  7. Disterhoft, J. F., and Olds, J. (1972): Differential development of conditioned unit changes in thalamus and cortex of rat. J. Neurophysiol. 35:665–679.PubMedGoogle Scholar
  8. Ellison, G.D., Sorenson, CA., and Jacobs, B. L. (1970): Two feeding syndromes following surgical isolation of the hypothalamus in rats. J. Comp. Physiol. Psychol. 70:173–188.PubMedCrossRefGoogle Scholar
  9. Fuxe, K. (1965): Evidence for the existence of monoamine neurons in the central nervous system. IV. Distribution of monoamine nerve terminals in the central nervous system. Acta Physiol. Scand. (Suppl.) 247:37–84Google Scholar
  10. Gallistel, C. R. (1973): Self-stimulation: The neurophysiology of reward and motivation. In: The Physiological Basis of Memory. Deutsch, J. A., ed. New York: Academic Press, pp. 175–267.Google Scholar
  11. Hamburg, M. D. (1971): Hypothalamic unit activity and eating behavior. Am. J. Physiol. 220: 980–985.PubMedGoogle Scholar
  12. Hebb, D. O. (1949): The Organization of Behavior. A Neuropsychological Theory. New York: John Wiley.Google Scholar
  13. Hoebel, B. G., and Teitelbaum, P. (1962): Hypothalamic control of feeding and self-stimulation. Science 135:375–377.PubMedCrossRefGoogle Scholar
  14. Hull, C. L. (1943): Principles of Behavior. New York: Appleton-Century-Crofts.Google Scholar
  15. Ito, M. (1972): Excitability of medial forebrain bundle neurons during self-stimulating behavior. J. Neurophysiol. 35:652–664.PubMedGoogle Scholar
  16. Ito, M., and Olds, J. (1971): Unit activity during self-stimulation behavior. J. Neurophysiol. 34: 263–273.PubMedGoogle Scholar
  17. Jasper, H. (1949): Diffuse projection systems: The integrative action of the thalamic reticular system. Electroencephalogr. Clin. Neurophysiol. 1:405–420.PubMedGoogle Scholar
  18. Keesey, R. E., and Powley, T. L. (1968): Enhanced lateral hypothalamic reward sensitivity following septal lesions in the rat. Physiol. Behav. 3:557–562.CrossRefGoogle Scholar
  19. Lindsley, D. B. (1951): Emotion. In: Handbook of Experimental Psychology. Stevens, S. S., ed. New York: John Wiley, pp. 473–516.Google Scholar
  20. Linseman, N. A., and Olds, J. (1973): Activity changes in rat hypothalamus, preoptic area, and striatum associated with Pavlovian conditioning. J. Neurophysiol. 36:1038–1050.PubMedGoogle Scholar
  21. Margules, D. L., and Olds, J. (1962): Identical “feeding” and “rewarding” systems in the lateral hypothalamus of rats. Science 135:374–375.PubMedCrossRefGoogle Scholar
  22. Marr, D. (1969): A theory of cerebellar cortex. J. Physiol. 202:437–470.PubMedGoogle Scholar
  23. Miller, N. E. (1957): Experiments on motivation. Science 126:1271–1278.PubMedCrossRefGoogle Scholar
  24. Miller, N. E., Roberts, W. W., and Delgado, J. M. R. (1953): Learning Motivated by Electrical Stimulation of the Brain (Motion picture shown by N. E. Miller at the Experimental Division of the American Psychological Assn., September 1953).Google Scholar
  25. Mulhouse, O. E. (1969): A Golgi study of the descending medial forebrain bundle. Brain Res. 15:341–363.CrossRefGoogle Scholar
  26. Moruzzi, G., and Magoun, H. W. (1949): Brain stem reticular formation and activation of the EEG. Electroencephalogr. Clin. Neurophysiol. 1:455–473.PubMedGoogle Scholar
  27. Norgren, R., and Leonard, C. M. (1973): Ascending central gustatory pathways. J. Comp. Neurol. 150:217–237.PubMedCrossRefGoogle Scholar
  28. Olds, J. (1956a): A preliminary mapping of electrical reinforcing effects in the rat brain. J. Comp. Physiol. Psychol. 49:281–285.PubMedCrossRefGoogle Scholar
  29. Olds, J. (1956b): Runway and maze behavior controlled by basomedial forebrain stimulation in the rat. J. Comp. Physiol. Psychol. 49:507–512.PubMedCrossRefGoogle Scholar
  30. Olds, J. (1958): Self-stimulation of the brain. Science 127:315–324.PubMedCrossRefGoogle Scholar
  31. Olds, J. (1962): Hypothalamic substrates of reward. Physiol. Rev. 42:554–604.PubMedGoogle Scholar
  32. Olds, J. (1972): Learning and the hippocampus. Rev. Can. Biol. 31 (Suppl.): 215–238.PubMedGoogle Scholar
  33. Olds, J. (1973a): Brain mechanisms of reinforcement learning. In:Pleasure, Reward, Preference. Their Nature, Determinants, and Role in Behavior. Berlyne, D. E., and Madsen, K. B., eds. New York: Academic Press, pp. 35–63.Google Scholar
  34. Olds, J. (1973b): The discovery of reward systems in the brain. In: Brain Stimulation and Motivation. Valenstein, E. S., ed. Glenview, Ill.: Scott, Foresman, pp. 81–99.Google Scholar
  35. Olds, J., Disterhoft, J. F., Segal, M., Kornblith, C. L., and Hirsh, R. (1972): Learning centers of rat brain mapped by measuring latencies of conditioned unit responses. J. Neurophysiol. 35:202–219.PubMedGoogle Scholar
  36. Olds, J., Killam, K. F., and Bach-y-Rita, P. (1956): Self-stimulation of the brain used as a screening method for tranquilizing drugs. Science 124:265–266.PubMedCrossRefGoogle Scholar
  37. Olds, J., and Milner, P. (1954): Positive reinforcement produced by electrical stimulation of septal area and other regions of rat brain. J. Comp. Physiol. Psychol. 47:419–427.PubMedCrossRefGoogle Scholar
  38. Olds, J., Mink, W. D., and Best, P.J. (1969): Single unit patterns during anticipatory behavior. Electroencephalogr. Clin. Neurophysiol. 26:144–158.PubMedCrossRefGoogle Scholar
  39. Olds, J., Travis, R. P., and Schwing, R. C. (1960): Topographic organization of hypothalamic self-stimulation functions. J. Comp. Physiol. Psychol. 53:23–32.PubMedCrossRefGoogle Scholar
  40. Olds, J., Yuwiler, A., Olds, M. E., and Yun, C. (1964): Neurohumors in hypothalamic substrates of reward. Am. J. Physiol. 207:242–254.PubMedGoogle Scholar
  41. Olds, M. E. (1972): Comparative effects of amphetamine, scopolamine and chlordiazepoxide on self-stimulation behavior. Rev. Can. Biol. 31 (Suppl.): 25–47.PubMedGoogle Scholar
  42. Olds, M. E. (1973): Short-term changes in the firing pattern of hypothalamic neurons during Pavlovian conditioning. Brain Res. 58:95–116.PubMedCrossRefGoogle Scholar
  43. Olds, M. E., and Ito, M. (1973): Noradrenergic and cholinergic action on neuronal activity during self-stimulation behavior in the rat. Neuropharmacology 12:525–539.PubMedCrossRefGoogle Scholar
  44. Olds, M. E., and Olds, J. (1962): Approach-escape interactions in rat brain. Am. J. Physiol. 203: 803–810.PubMedGoogle Scholar
  45. Olds, M. E., and Olds, J. (1963): Approach-avoidance analysis of rat diencephalon. J. Comp. Neurol. 120:259–295.PubMedCrossRefGoogle Scholar
  46. Roberts, W. W. (1958): Both rewarding and punishing effects from stimulation of posterior hypothalamus of cat with same electrode at same intensity. J. Comp. Physiol. Psychol. 51:400–407.PubMedCrossRefGoogle Scholar
  47. Routtenberg, A. (1971): Forebrain pathways of reward in Rattus norvegiens. J. Comp. Physiol. Psychol. 75:269–276.CrossRefGoogle Scholar
  48. Routtenberg, A., and Malsbury, C. (1969): Brainstem pathways of reward. J. Comp. Physiol. Psychol. 68:22–30.PubMedCrossRefGoogle Scholar
  49. Scott, J. W., and Pfaffmann, G. (1967): Olfactory input t the hypothalamus: Electrophysiological evidence. Science 158:1592–1594.PubMedCrossRefGoogle Scholar
  50. Segal, M. (1973): Flow of conditioned responses in limbic telencephalic system of the rat. J. Neurophysiol. 36:840–854.PubMedGoogle Scholar
  51. Segal, M., Disterhoft, J. F., and Olds, J. (1972): Hippocampal unit activity during classical aversive and appetitive conditioning. Science 175:792–794.PubMedCrossRefGoogle Scholar
  52. Segal, M., and Olds, J. (1972): Behavior of units in hippocampal circuit of the rat during learning. J. Neurophysiol. 35:680–690.PubMedGoogle Scholar
  53. Skinner, B. F. (1938): The Behavior of Organisms. New York: Appleton-Century-Crofts.Google Scholar
  54. Solomon, R. L., and Wynne, L. G. (1954): Traumatic avoidance learning: The principles of anxiety conservation and partial irreversibility. Psychol. Rev. 61:353–385.PubMedCrossRefGoogle Scholar
  55. Stark, P., and Boyd, E. S. (1963): Effects of cholinergic drugs on hypothalamic self-stimulation response rates of dogs. Am. J. Physiol. 205:745–748.PubMedGoogle Scholar
  56. Stein, L. (1964a): Amphetamine and neural reward mechanisms. In: Animal Behaviour and Drug Action (Giba Foundation Symposium). Steinberg, H., ed. Boston: Little, Brown, pp. 91–118.Google Scholar
  57. Stein, L. (1964b): Effects and interactions of imipramine, chlorpromazine, reserpine, and amphetamine on self-stimulation: Possible neurophysiological basis of depression. In: Recent Advances in Biological Psychiatry. Wortis, J., ed. New York: Plenum Press, pp. 288–308.Google Scholar
  58. Stein, L. (1968): Chemistry of reward and punishment. In: Psychopharmacology. A Review of Progress, 1957–1967. Efron, D. H., editor-in-chief. Washington, D. C.: U. S. Government Printing Office, pp. 105–123.Google Scholar
  59. Tolman, E. C. (1949): Purposive Behavior in Animals and Men. Berkeley: University of California Press.Google Scholar
  60. Valenstein, E. S. (1973): Commentary. In: Brain Stimulation and Motivation. Valenstein, E. S., ed. Glenview, Ill.: Scott, Foresman, pp. 162–172.Google Scholar
  61. Wise, C. D., Berger, B. D., and Stein, L. (1973): Evidence of a-noradrenergic reward receptors and serotonergic punishment receptors in the rat brain. Biol. Psychiatry 6:3–21.PubMedGoogle Scholar

Copyright information

© Birkhäuser Boston 1992

Authors and Affiliations

  • James Olds

There are no affiliations available

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