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Derivatization of Cells with Antibody

  • Anna Ratner
  • William R. Clark

Abstract

This technique is very useful for redirected lysis of target cells which are otherwise not recognized by a particular CTL. Target cells are derivatized with antibody specific either for the α- or β-chain of the T-cell receptor (TCR), or for a member of the CD-3 complex of TCR-associated proteins. Useful control antibodies are class I or CD-8, neither of which should induce target cell lysis.

Keywords

Target Cell Room Tempera Sulfhydryl Group Cytotoxic Cell Molar Excess 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Copyright information

© Birkhäuser Boston 1993

Authors and Affiliations

  • Anna Ratner
  • William R. Clark

There are no affiliations available

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