Ontogenetic Development and Decline of Memory Functions in Nonhuman Primates

  • Jocelyne Bachevalier
  • Mortimer Mishkin


An emerging parallel view in research on ontogeny and decline of memory abilities is that mnemonic processes are differentially susceptible to age. Some behavioral memory tasks are performed normally by newborn monkeys, whereas other memory tasks are performed normally only if the animal is mature. Similarly, some memory tasks are performed normally by aged subjects while other tasks are not. Thus, it appears that the presence and absence of age-related memory abilities depend on the specific information-processing demands of the behavioral tasks used to measure memory functions. One important outcome of characterizing impaired versus preserved memory function in ontogeny or aging is the insight this information can provide concerning the neural systems that mediate age-dependent cognitive functions. Neuropsychological findings in amnesic patients and in monkeys with experimental brain damage have indicated that different brain regions appear to make rather specialized contributions to learning and memory. Accordingly, specific types of cognitive abilities in infant and aged subjects may reflect the functional status of those brain regions that mediate the component processes of memory. Based on this neuropsychological perspective, this chapter will review actual knowledge on the ability of both infant, mature, and aged monkeys to form habits and memories, two learning processes that are known to depend on separate neural circuits.


Medial Temporal Lobe Visual Recognition Amnesic Patient Inferior Temporal Cortex Aged Monkey 


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© Birkhäuser Boston 1992

Authors and Affiliations

  • Jocelyne Bachevalier
  • Mortimer Mishkin

There are no affiliations available

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