Motor Activity and Antidepressant Drugs: A Proposed Approach to Categorizing Depression Syndromes and Their Animal Models

  • Martin H. Teicher
  • Natacha I. Barber
  • Janet M. Lawrence
  • Ross J. Baldessarini


Affective disorders are characterized by disturbances in mood, cognition, and neurovegetative processes. Among the latter, dysregulation of appetite and weight, sleep, energy, and libido have received particular clinical attention. Current standard diagnostic criteria for major depression in the American Psychiatric Association Diagnostic Manual (DSM-III) accommodate neurovegetative disturbances in either direction—deficits as well as excesses—and evaluation of these features is routine in the clinical assessment of depressed patients. These dysfunctions often serve as target symptoms for psychopharmacological treatment and as quantifiable behaviors that can be used to bridge the gap between animal models and relevant clinical disorders.


Antidepressant Drug Activity Rhythm Bipolar Patient Maternal Separation Ultradian Rhythm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Birkhäuser Boston 1989

Authors and Affiliations

  • Martin H. Teicher
  • Natacha I. Barber
  • Janet M. Lawrence
  • Ross J. Baldessarini

There are no affiliations available

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