• Tsuneo Fujita
Part of the Readings from the Encyclopedia of Neuroscience book series (REN)


Paraneurons (a term originated by Fujita in 1975) are groups of cells which have not been classified as neurons and yet share certain morphological and functional features with neurons. Paraneurons are defined by three criteria: (1) They possess neurosecretion-like and/or synaptic-vesicle-like granules. (2) They produce substances identical with or related to neurosecretions or neurotransmitters. (3) They recognize adequate stimuli and respond to them by the release of their secretions. As item (3) indicates, paraneurons can be characterized as receptosecretory cells. If the receptive function of a cell appears dominant, it can be called a sensory paraneuron. If the secretory function comes to the front, the cell can be called a secretory or endocrine paraneuron.


Hair Cell Endocrine Cell Carotid Body Bioactive Peptide Gustatory Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Further reading

  1. Fujita T (1977): Concept of paraneurons. Arch Histol Jpn 40:1–12Google Scholar
  2. Fujita T, et al. (1979): Current views on the paraneuron concept. Trend Neurosci 2:27–30CrossRefGoogle Scholar
  3. Fujita T (1983): Messenger substances of neurons and paraneurons: their chemical nature and the routes and ranges of their transport to targets. Biomed Res 4:239–256Google Scholar
  4. Fujita T, et al. (1983): Immunohistochemical detection of nervous system-specific proteins in normal and neoplastic paraneurons in the gut and pancreas. In: Gut Peptides and Ulcer, Miyoshi A ed. Tokyo: Biomedical Research FoundationGoogle Scholar

Copyright information

© Birkhäuser Boston, Inc. 1988

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  • Tsuneo Fujita

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