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Gene Function pp 110-155 | Cite as

Mutation

  • Robert E. Glass

Abstract

The genetic material of an organism (be it DNA or RNA1) may be damaged during growth by factors in its external or internal environment. A heritable change that permanently affects the chromosome, termed a mutation, results in an altered, mutant organism. Mutations in a particular gene give rise to a number of different alleles of that gene; these homologues may differ in one or more nucleotide pairs. The selective advantage that any one allele imparts to the mutant strain allows its preferential survival. Non-lethal chromosomal lesions (see below) are the source of genetic variation and, thus, provide the basis for evolution.

Keywords

Frameshift Mutation Genetic Lesion Base Analogue Nonsense Suppression Nonsense Codon 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Bibliography

Mutation Classification

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Mutagenesis

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Copyright information

© Robert E. Glass 1982

Authors and Affiliations

  • Robert E. Glass
    • 1
  1. 1.NottinghamUK

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