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Lipids

  • Luciano Cominacini
  • Ulisse Garbin
  • Anna Davoli
  • Beatrice Cenci
  • Ottavio Bosello

Abstract

The relations between elevated cholesterol concentration and coronary heart disease is known to physicians as the lipid hypothesis. This theory breaks cholesterol into two components: low-density lipoprotein (LDL) or “bad” cholesterol and high-density lipoprotein (HDL) or “good” cholesterol. LDL usually deposits cholesterol on the inner walls of the arteries, whereas HDL works in the opposite manner. Therefore, a person who has a high total cholesterol and LDL level and a low level of HDL has an increased risk of developing coronary heart disease.

Keywords

Coronary Heart Disease Dietary Fiber Plasma Lipid Mediterranean Diet Glycemic Index 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Ahrens, E. H., J. Hirsh, K. Oette, J. W. Farquhar, and Y. Stein. 1967. Carbohydrate-induced and fat-induced lipemia. Trans. Assoc. Am. Phys. 74:134–144.Google Scholar
  2. Albers, J. J., M. C. Cheung, and W. R. Hazzard. 1978. High density lipoprotein in myocardial infarction survivors. Metabolism 27:479–487.PubMedCrossRefGoogle Scholar
  3. Albrink, M. J., T. Newman, and P. C. Davidson. 1979. Effect of high-and lowfiber diets on plasma lipids and insulin. Am. J. Clin. Nutr. 32:1486–1491.PubMedGoogle Scholar
  4. Anderson, J. W., and W. L. Chen. 1979. Plant fiber. Carbohydrate and lipid metabolism. Am. J. Clin. Nutr. 32:346–363.PubMedGoogle Scholar
  5. Anderson, J. W., W. J. L. Chen, and B. Sieling. 1980. Hypolipidemic effects of high-carbohydrate, high-fiber diets. Metabolism 29:551–558.PubMedCrossRefGoogle Scholar
  6. Ascaso, J. F., S. Serrano, and J. Martinez. 1987. Effecto del aceite de oliva de la dieta sobre las HDL. Rev. Clin. Eso. 180:486–488.Google Scholar
  7. Behall, K. M., K. H. Lee, and R B. Mose. 1984. Blood lipids and lipoproteins in adult men fed four refined fibres. Am. J. Clin. Nutr. 39:209–214.PubMedGoogle Scholar
  8. Bhathena, S. J., J. Avigan, and M. E. Schreiner. 1974. Effect of insulin on sterol and fatty acids synthesis and hydroxymethylglutaryl coA reductase activity in mammalian cells grown in culture. Proc. Natl. Acad. Sci. 71:2174–2178.PubMedCrossRefGoogle Scholar
  9. Blum, C. B., R. I. Levy, S. Eisemberg, M. Hall, R. H. Goebel, and M. Berman. 1977. High density lipoprotein metabolism in man. J. Clin. Invest. 60:795–807.PubMedCrossRefGoogle Scholar
  10. Bosello, O., M. Cigolini, A. Battaglia, F. Ferrari, R. Micciolo, R. Olivetti, and M. Corsato. 1984a. Adipose tissue lipoprotein lipase in obesity. Int. J. Obesity 8:213–220.Google Scholar
  11. Bosello, O., L. Cominacini, I. Zocca, U. Garbin, F. Ferrari, and A. Davoli. 1984b. Effects of guar gum on plasma lipoproteins and apolipoproteins C-II and C-III in patients affected by familial combined hyperlipoproteinemia. Am. J. Clin. Nutr. 40:1165–1174.Google Scholar
  12. Bosello, O., L. Cominacini, I. Zocca, U. Garbin, A. Davoli, and F. Ferrari. 1985. High density lipoprotein subfractions during semistarvation in obese women. Ann. Nutr. Metab. 29:381–386.PubMedCrossRefGoogle Scholar
  13. Bosello, O., L. Cominacini, I. Zocca, U. Garbin, R. Compri, A. Davoli, and L. Brunetti. 1988. Short-and long-term effects of hypocaloric diet containing proteins of different sources on plasma lipids and apoproteins of obese subjects. Ann. Nutr. Metab. 32:206–214.PubMedCrossRefGoogle Scholar
  14. Brownell, K. D., and A. J. Stunkard. 1981. Differential changes in plasma high-density lipoprotein-cholesterol levels in obese men and women during weight reduction. Arch. Intern. Med. 141:1141–1146.CrossRefGoogle Scholar
  15. Burkitt, D. P. 1973. Some disease characteristics of modern Western civilisation. Br. Med. J. 1:424–430.CrossRefGoogle Scholar
  16. Carmena, R. 1989. Monounsaturated fatty acids: a critical appraisal. In Atherosclerosis VIII, G. Crepaldi, A. M. Lotto, E. Manazato, and G. Baggio, eds., pp. 679–682. Amsterdam: Elsevier.Google Scholar
  17. Carroll, K. K., P. M. Giovannetti, M. W. Huff, O. Moase, D. C. K. Roberts, and B. M. Wolfe. 1978. Hypocholesterolemic effect of substituting soybean protein for animal protein in the diet of healthy young women. Am. J. Clin. Nutr. 31:1312–1321.Google Scholar
  18. Castelli, W. P., J. T. Doyle, T. Gordon, C. G. Hames, M. C. Hjortland, S. B. Hulley, A. Kagan, W. J. Zukel. 1977. HDL-cholesterol and other lipids in coronary heart disease. The cooperative lipoprotein phenotyping study. Circulation 55:767–772.PubMedGoogle Scholar
  19. Cohen, A. M., N. A. Kaufmann, and R. Poznansky. 1966. Effect of starch and sucrose on carbohydrate-induced hyperlipaemia. Br. Med. J. 1:339–340.PubMedCrossRefGoogle Scholar
  20. Cohn, J. S., W. G. Kimpton, and P. J. Nestel. 1984. The effect of dietary casein and soy protein on cholesterol and very low density lipoprotein metabolism in the rat. Atherosclerosis 52:219–231.PubMedCrossRefGoogle Scholar
  21. Cominacini, L., I. Zocca, U. Garbin, A. Davoli, R. Micciolo, P. De Bastiani, and O. Bosello. 1988a. High density lipoprotein composition in obesity: interrelationships with plasma insulin levels and body weight. Int. J. Obesity 12:343–352.Google Scholar
  22. Cominacini, L., I. Zocca, U. Garbin, A. Davoli, R. Compri, L. Brunetti, and O. Bosello. 1988b. Long-term effect of a low-fat, high-carbohydrate diet on plasma lipids of patients affected by familial endogenous hypertriglyceridemia. Am. J. Clin. Nutr. 48:57–65.Google Scholar
  23. Cominacini, L., I. Zocca, U. Garbin, A. Davoli, L. Brunetti, M. Zamboni, C. Smacchia, R. Compri, and O. Bosello, 1988e. Effect of a low-fat, highcomplex-carbohydrate diet on insulin response and plasma lipids in patients affected by endogenous hypertriglyceridemia. Clin. Nutr. 10:54–59.Google Scholar
  24. Cominacini, L., O. Bosello, U. Garbin, A. Davoli, L. Brunetti, and L. A. Scuro. 1990. Comparison of a low-fat, high-carbohydrate diet at two levels of polyunsaturates on plasma lipids of patients with familial endogenous hypertriglyceridemia. J. Nutr. Med. 1:95–105.CrossRefGoogle Scholar
  25. Consensus Development Conference. 1985. Lowering blood cholesterol to prevent heart disease. JAMA 253:2080–2086.CrossRefGoogle Scholar
  26. Cooper, A. D., and M. A. Shrewsbury. 1979. Effects of chilomicron remnants on hepatic lipoprotein metabolism. Clin. Res. 27:363 (abstract).Google Scholar
  27. Coulston, A. M., G. C. Liu, and G. M. Reaven. 1983. Plasma glucose, insulin and lipid response to high-carbohydrate, low-fat diets in normal humans. Metabolism 32:52–56.PubMedCrossRefGoogle Scholar
  28. Crapo, P. A. 1985. Simple versus complex carbohydrate use in the diabetic diet. Ann. Rev. Nutr. 5:95–114.CrossRefGoogle Scholar
  29. Crapo, P. A., G. Reaven, and J. Olefsky. 1976. Plasma glucose and insulin responses to orally administered simple and complex carbohydrates. Diabetes 25:741–747.PubMedCrossRefGoogle Scholar
  30. Crapo, P. A., G. Reaven, and J. Olefsky. 1977. Postprandial plasma-glucose and insulin responses to different complex carbohydrates. Diabetes 26:1178–1183.PubMedCrossRefGoogle Scholar
  31. Cresta, M., S. Lederman, A. Gamier, E. Lombardo, and G. Lacourly. 1969. Etude des consommations alimentaires des populations de onze régions de la communauté européenne en vue de la détermination des niveaux de la contamination radioactive. Rapport établi au centre d’Etude Nucléaire de Fontenay-aux-Roses, France: EURATOM, Commissariat à l’énergie atomique (C.E.A.)Google Scholar
  32. Delbarre, F. J., J. Fondier, and A. De Gery. 1977. Lack of effect of two pectins on idiopathic or gout-associated hyperdyslipidemic hypercholesterolemia. Am. J. Clin. Nutr. 30:463–464.PubMedGoogle Scholar
  33. Durrington, P. N., J. P. Manning, C. H. Bolton, and M. Hartog. 1976. Effect of pectin on serum lipids and lipoproteins, whole gut transit time and stool weight. Lancet 2:393–396.Google Scholar
  34. Ernest, I., B. Hallgren, and A. Svanborg. 1962. Short term study of effect of different isocaloric diets in diabetes. Metabolism 11:912–919.Google Scholar
  35. Ernest, I., E. Linner, and A. Svanborg. 1965. Carbohydrate-rich, fat-poor diet in diabetes. Am. J. Med. 39:594–602.PubMedCrossRefGoogle Scholar
  36. Fahrenbach, M. H., B. A. Riccardi, J. C. Saunders, N. Lourie, and J. C. Heider. 1965. Comparative effects of guar gum and pectin on human serum cholesterol levels. Circulation 31 (Suppl. II): 11–14.Google Scholar
  37. Fisher, H., P. Griminger, E. R. Sostman, and M. K. Brush. 1965. Dietary pectin and plasma cholesterol. J. Nutr. 86:113–118.PubMedGoogle Scholar
  38. Forman, D. T., J. E. Garvin, J. E. Forestner, and C. B. Taylor. 1968. Increased excretion of faecal bile acids by an oral hydrophilic colloid. Proc. Soc. Exp. Med. 127:1060–1063.Google Scholar
  39. Fumagalli, R., R. Soleri, R. Farina, R. Musanti, O. Mantero, G. Noseda, E. Gatti, and C. R. Sirtori. 1982. Fecal cholesterol excretion studies in type II hypercholesterolemic patients treated with the soybean protein diet. Atherosclerosis 43:341–350.PubMedCrossRefGoogle Scholar
  40. Galeotti, G. 1936. Primi risultati dell’ inchiesta alimentare condotta in varie provincie d’Italia. Quaderni della Nutrizione 3(1).Google Scholar
  41. Gammal, E. B., K. K. Carroll, and E. R. Plunkett. 1967. Effects of dietary fat on mammary carcinogenesis by 7, 12-dimethylbenz(alpha)anthracene in rats. Cancer Res. 27:1737–1742.PubMedGoogle Scholar
  42. Ginsberg, H., J. M. Olefsky, G. Kimmerling, P. Crapo, and G. M. Reaven. 1976. Induction of hypertriglyceridemia by a low-fat diet. J. Clin. Endocr. Metab. 42:729–735.PubMedCrossRefGoogle Scholar
  43. Gonen, B., W. Patsch, I. Kuisk, and G. Schonfeld. 1981. The effect of short-term feeding of high carbohydrate diet on HDL subclasses in normal subjects. Metabolism 30:1125–1129.PubMedCrossRefGoogle Scholar
  44. Gordon, T., W. Kannel, W. P. Castelli, and T. R. Dawber. 1981. Lipoproteins, cardiovascular disease and death. The Framingham Study. Arch. Intern. Med. 141:1128–1131.PubMedCrossRefGoogle Scholar
  45. Green, M. H., E. R. Massaro, and J. B. Green. 1984. Multicompartmental analysis of the effects of dietary fat saturation and cholesterol on absorptive lipoprotein metabolism in the rat. Am. J. Clin. Nutr. 40:82–94.PubMedGoogle Scholar
  46. Grundy, S. M. 1986. Comparison of monounsaturated fatty acids and carbohydrates for lowering plasma cholesterol. N. Engl. J. Med. 314:745–748.PubMedCrossRefGoogle Scholar
  47. Grundy, S. M. 1989. What is the desirable fat intake? In Atherosclerosis VIII, G. Crepaldi, A. M. Gotto, E. Manzato, and G. Baggio, eds., pp. 665–672. Amsterdam: Elsevier.Google Scholar
  48. Grundy, S. M., and A. Bonanome. 1987. Summary of the Second Colloquium on Monounsaturates, Bethesda, 1987. Arteriosclerosis 7:644–648.Google Scholar
  49. Hayford, J. T., M. M. Danney, D. Wiebe, S. Roberts, and R. G. Thompson. 1979. Triglyceride integrated concentrations: effect of variation of source and amount of dietary carbohydrate. Am. J. Clin. Nutr. 32:1670–1678.PubMedGoogle Scholar
  50. Hegsted, D. M., R. B. Mc Gandy, M. L. Myers, and F. J. Stare. 1965. Quantitative effects of dietery fat on serum cholesterol in man. Am. J. Clin. Nutr. 17:281–295.PubMedGoogle Scholar
  51. Hjerman, I. 1981. Effect of diet and smoking intervention on the incidence of coronary heart disease. Report from the Oslo Study Group of a randomized trial in healthy men. Lancet 2(8259):1303–1310.CrossRefGoogle Scholar
  52. Hollenbeck, C. B., M. C. Riddle, W. E. Connor, and J. E. Leklem. 1985. The effects of subject-selected high carbohydrate, low fat diets on glycemic control in insulin dependent diabetes mellitus. Am. J. Clin. Nutr. 41:293–298.PubMedGoogle Scholar
  53. Holmes, H. L., G. B. Rubel, and S. S. Hood. 1980. Comparison of the effect of dietary meat versus dietary soybean protein on plasma lipids of hyperlipidemic individuals. Atherosclerosis 36:379–387.CrossRefGoogle Scholar
  54. Huff, M. W., and K. K. Carrol. 1980. Effects of dietary protein turnover, oxidation and absorption of cholesterol on steroid excretion in rabbits. J. Lipid Res. 21:546–558.PubMedGoogle Scholar
  55. Huff, M. W., R. M. G. Hamilton, and K. K. Carrol. 1977. Plasma cholesterol levels in rabbits fed low-fat, cholesterol-free, semipurified diets: effects of dietary protein hydrolysate and amino acid mixtures. Atherosclerosis 28:187–195.PubMedCrossRefGoogle Scholar
  56. Huff, M. W., P. M. Giovannetti, and B. M. Wolfe. 1984. Turnover of very low-density lipoprotein-apoprotein B is increased by substitution of soybean protein for meat and dairy protein in the diets of hypercholesterolemic men. Am. J. Clin. Nutr. 39:888–897.PubMedGoogle Scholar
  57. Irie, N., T. Hara, and Y. Goto. 1982. The effects of guar gum on post-prandial chylomicronemia. Nutr. Rep. Int. 26:207–214.Google Scholar
  58. Jacotot, B., M. F. Baudet, and M. Lasserre. 1988. Olive oil and the lipoprotein metabolism. Rev. Fran. Corps Gras. 35:51–56.Google Scholar
  59. Jenkins, D. J. A. 1977. Action of dietary fibre in lowering fasting serum cholesterol and reducing post-prandial glycemia. In International Conference on Atherosclerosis, L. A. Carlson, R. Paoletti, and G. Weber, eds., pp. 173–178. New York: Raven Press.Google Scholar
  60. Jenkins, D. J. A., 1982. Lente carbohydrate: a new approach to the dietary management of diabetes. Diabetes Care 5:634–641.PubMedCrossRefGoogle Scholar
  61. Jenkins, D. J. A., M. S. Hill, and J. K. Cummings. 1975a. Effect of wheat fiber on blood lipids, fecal steroid excretion and serum iron. Am. J. Clin. Nutr. 28:1408–1411.Google Scholar
  62. Jenkins, D. J. A., A. R. Leeds, C. Newton, and J. H. Cumming. 1975b. Effect of pectin, guar gum and wheat fibre on serum cholesterol. Lancet 1:1116–1117.CrossRefGoogle Scholar
  63. Jenkins, D. J. A., A. R. Leeds, M. A. Gassul, H. Houston, D. V. Goff, and M. J. Hill. 1976. The cholesterol lowering effect of guar and pectin. Clin. Sci. Mol. Med. 51:8–12.Google Scholar
  64. Jenkins, D. J. A., A. R. Leeds, B. Slavin, J. Man, and E. M. Jepson.1979a. Dietary fibre and blood lipids: reduction of serum cholesterol in Type II hyperlipidemia by guar gum. Am. J. Clin. Nutr. 32:16–18.Google Scholar
  65. Jenkins, D. J. A., D. Reynolds, A. R. Leeds, A. L. Waller, and J. H. Cummings. 1979b. Hypocholesterolemic action of dietary fibre unrelated to fecal bulking effect. Am. J. Clin. Nutr. 32:2430–2435.Google Scholar
  66. Jenkins, D. J. A., S. R. Bloom, R. H. Albuquerque, A. R. Leeds, D. L. Sarson, G. L. Metz, and K. G. M. M. Alberti. 1980. Pectin and complications of gastric surgery: normalisation of post-prandial glucose and endocrine responses. Gut 21:574–579.PubMedCrossRefGoogle Scholar
  67. Jenkins, D. J. A., T. M. S. Wolever, and R. H. Taylor. 1981. Glycemic index of foods: a physiological basis for carbohydrate exchange. Am. J. Clin. Nutr. 34:362–366.PubMedGoogle Scholar
  68. Jenkins, D. J. A., T. M. S. Wolever, A. L. Jenkins, R. Lee, G. S. Wong, and R. Josse. 1983a. Glycemic response to wheat products: reduced response to pasta but no effect of fiber. Diabetes Care 1:155–159.CrossRefGoogle Scholar
  69. Jenkins, D. J. A., G. S. Wong, R. Pattern, J. Bird, M. Hall, G. C. Buckley, V. McGuire, R. Reichart, and J. A. Little. 1983b. Leguminous seeds in the dietary management of hyperlipidemia. Am. J. Clin. Nutr. 38:567–573.Google Scholar
  70. Jenkins, D. J. A., T. M. S. Wolever, A. L. Jenkins, R. G. Josse, and G. S. Wong. 1984. The glycemic response to carbohydrate foods. Lancet 2:388–391.PubMedCrossRefGoogle Scholar
  71. Jenkins, D. J. A., T. M. S. Wolever, and J. Kalmusky. 1985. Low glycemic index foods in the management of hyperlipidemia. Am. J. Clin. Nutr. 42:604–617.PubMedGoogle Scholar
  72. Judd, P. A. and A. S. Truswell. 1982. Comparison of the effects of high-and low-methoxyl pectins on blood and fecal lipids in man. Br. J. Nutr. 48:451–458.PubMedCrossRefGoogle Scholar
  73. Judd, P. A. and A. S. Truswell. 1985. Dietary fibre and blood lipids in man. In Dietary Fibre Perspectives. A. R. Leeds, ed., pp. 23–39. London: John Libbey.Google Scholar
  74. Kannel, W. B., W. P. Castelli, and T. Gordon. 1979. Cholesterol in the prediction of atherosclerotic disease. New perspectives based on the Framingham Study. Ann. Intern. Med. 90:85–91.PubMedGoogle Scholar
  75. Kashyap, M. L., R. L. Barnhart, and S. Srivastava. 1982. Effects of dietary carbohydrate and fat on plasma lipoproteins and apolipoproteins C-II and C-III in healthy men. J. Lip. Res. 23:877–886.Google Scholar
  76. Kato, H., J. Tillotson, M. Nichman, G. Rhoades, and H. Hamilton. 1973. Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California: Serum lipids and diet. Amer. J. Epidemiol. 97:372–380.Google Scholar
  77. Kaufmann, N. A., S. R. Poznansky, S. H. Blondheim, and Y. Stein. 1966. Changes in serum lipid levels of hyperlipemic patients following the feeding of starch, sucrose and glucose. Am. J. Clin. Nutr. 18:261–269.PubMedGoogle Scholar
  78. Kay, R. M. 1982. Dietary fiber. J. Lipid Res. 23:221–242.PubMedGoogle Scholar
  79. Keys, A., J. T. Anderson, and F. Grande. 1957. Prediction of serum-cholesterol responses of man to changes in fats in the diet. Lancet 2:959–969.CrossRefGoogle Scholar
  80. Keys, A., J. T. Anderson, and F. Grande. 1969. Serum-cholesterol response to changes in the diet. II. The effect of cholesterol in the diet. Metabolism 14:759–765.CrossRefGoogle Scholar
  81. Keys, A. 1970. Coronary heart disease in seven countries. Circulation 41 (supplement): 1–10.Google Scholar
  82. Keys, A. 1975. Coronary heart disease. The global picture. Atherosclerosis 22:149–156.PubMedCrossRefGoogle Scholar
  83. Keys, A. 1980. Seven Countries. A multivariate analysis of death and coronary heart disease. Cambridge, Mass.: Harvard University Press.Google Scholar
  84. Kiehm, T. G., J. W. Anderson, and K. Ward. 1976. Beneficial effects of a high carbohydrate, high fiber diet on hyperglycemic diabetic men. Am. J. Clin. Nutr. 29:895–899.PubMedGoogle Scholar
  85. Kim, D. N., K. T. Lee, and W. A. Thomas. 1978. Effect of soy protein on serum cholesterol in swine fed fat and cholesterol. Exp. Mol. Pathol. 29:385–389.PubMedCrossRefGoogle Scholar
  86. King, M. E. and A. A. Spector. 1978. Effect of specific fatty acyl enrichments on membrane physical properties detected with a spin label probe. J. Biol. Chem. 253:6493–6501.PubMedGoogle Scholar
  87. Kirby, R. W., J. W. Anderson, B. Sieling, E. D. Rees, W. J. L. Chen, R. E. Miller, and R. M. Kay. 1981. Oat bran selectivity lowers serum low-density lipoprotein concentration: studies of hypercholesterolemic men. Am. J. Clin. Nutr. 34:824–829.PubMedGoogle Scholar
  88. Kritchevsky, D. 1979. Vegetable protein and atherosclerosis. J. Amer. Oil Chem. Soc. 56:135–139.CrossRefGoogle Scholar
  89. Kuo, P. T., and D. R. Basset. 1965. Dietary sugar in the production of hypertriglyceridemia. Ann. Intern. Med. 62:1199–1212.PubMedGoogle Scholar
  90. Langley, N. J., and F. W. Thye. 1977. The effect of wheat bran and/or citrus pectin on serum cholesterol and triglycerides in middle aged men. Fed. Proc. 36:11–18 (abstract).Google Scholar
  91. Levine, A. S., and S. E. Silvis. 1980. Absorption of whole peanuts, peanut oil and peanut butter. N. Engl. J. Med. 303:1729–1733.Google Scholar
  92. Levy, R. I. 1983. Intervention on single risk factors. hyperlipoproteinemia. In Atherosclerosis VI, G. Schettler, A. M. Gotto, G. Middelhoff, A. J. R. Habenicht, and K. R. Jurutka, eds., pp. 759–766. Berlin:Springer-Verlag.Google Scholar
  93. Levy, R. J., R. S. Lees, and D. S. Frederickson. 1966. The nature of pre-beta (very low-density) lipoproteins. J. Clin. Invest. 45:63–77.PubMedCrossRefGoogle Scholar
  94. Lipid Research Clinics Program. 1984. The Lipid Research Clinics Coronary Prevention Trial results: II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. JAMA 251:365–374.CrossRefGoogle Scholar
  95. Lithell, H., I. Jacobs, B. Vessby, K. Hellsing, and J. Karlsson. 1982. Decrease of lipoprotein lipase activity in skeletal muscle during a short-term carbohydrate-rich dietary regime. With special reference to HDL-cholesterol, apolipoprotein and insulin concentration. Metabolism 31:994–998.PubMedCrossRefGoogle Scholar
  96. Liu, G. C., A. M. Coulston, and G. M. Reaven. 1983. Effect of high carbohydrate-low fat diets on plasma glucose, insulin and lipid responses in hypertriglyceridemic humans. Metabolism 32:750–753.PubMedCrossRefGoogle Scholar
  97. Lovati, M. R., C. Manzoni, A. Canavesi, M. Sirtori, V. Vaccarino, M. Marchi, G. Gaddi, and C. R. Sirtori. 1987. Soybean protein diet increases low density lipoprotein receptor activity in mononuclear cells from hypercholesterolemic patients. J. Clin. Invest. 80:1498–1502.PubMedCrossRefGoogle Scholar
  98. MacDonald, I., and D. M. Braithwaite. 1964. The influence of dietary carbohydrate on the lipid pattern in serum and in adipose tissue. Clin. Sci. 27:23–30.PubMedGoogle Scholar
  99. Malhotra, S. L. 1967. Serum lipids, dietary factors and ischemic heart disease. Am. J. Clin. Nutr. 20:462–474.PubMedGoogle Scholar
  100. Marks, V., and D. S. Turner. 1977. The gastrointestinal hormones with particular reference to their role in the regulation of insulin secretion. Essay Biochem. 3:109–152.Google Scholar
  101. Mattson, F. H., and S. M. Grundy. 1985. Comparison of effects of dietary saturated, monounsaturated and polyunsaturated fatty acids on plasma lipids and lipoproteins in man. J. Lipid Res. 26:194–202.PubMedGoogle Scholar
  102. McGandy, R. B., D. M. Hegsted, M. L. Myers, and F. J. Stare. 1966. Dietary carbohydrate and serum cholesterol levels in man. Am. J. Clin. Nutr. 18: 237–242.PubMedGoogle Scholar
  103. Mensink, R. P., and M. B. Katan. 1987. Effect of monounsaturated fatty acids versus complex carbohydrates on high-density lipoproteins in healthy men and women. Lancet 1:122–125.PubMedCrossRefGoogle Scholar
  104. Miettinen, R. A., and S. Tarpila. 1977. Effect of pectin on serum cholesterol, fecal bile acids and biliary lipids in normolipidemic and hyperlipidemic individuals. Clin. Chim. Acta 79:471–477.PubMedCrossRefGoogle Scholar
  105. Miettinen, R. A. 1983. Effects of dietary fiber on cholesterol metabolism in man. In Fibre in Human and Animal Nutrition, G. Wallace and L. Bell, eds., pp. 173–177. Roy. Soc. N.Z. Bull. 20.Google Scholar
  106. Miller, G. J., and N. E. Miller. 1975. Plasma high density lipoprotein concentration and development of ischaemic heart disease. Lancet 1:16–19.PubMedCrossRefGoogle Scholar
  107. Morgan, L. M., I. J. Goulder, D. Tsiolakis, V. Marks, and K. G. M. M. Alberti. 1979. The effect of unabsorbable carbohydrates on gut hormones. Diabetologia 17:85–89.PubMedCrossRefGoogle Scholar
  108. Munoz, J. 1984. Fiber and diabetes. Diabetes Care 7:297–298.PubMedGoogle Scholar
  109. Nestel, P. J., K. F. Carrol, and N. Havenstein. 1970. Plasma triglyceride response to carbohydrates, fats and caloric intake. Metabolism 19:1–18.PubMedCrossRefGoogle Scholar
  110. Nestel, P. J., M. Rearden, and N. H. Fidge. 1979. Sucrose-induced changes in VLDL- and LDL-B apoprotein removal rates. Metabolism 28:531–535.PubMedCrossRefGoogle Scholar
  111. Niceforo, A., and G. Galeotti. 1943. Primi risultati dell’ inchiesta alimentare condotta in varie provincie d’Italia. Quaderni della Nutrizione 1(1).Google Scholar
  112. Nikkila, E. A., and M. Kekki. 1972. Effects of dietary fructose and sucrose in plasma triglyceride metabolism in patients with endogenous hyper-triglyceridemia. Acta Med. Scand. 542 (suppl):221–229.Google Scholar
  113. Nikkila, E. A., M. R. Taskinen, and M. Kekki. 1978. Relation of plasma high density lipoprotein cholesterol to lipoprotein-lipase activity in adipose tissue and skeletal muscle of man. Atherosclerosis 29:497–501.PubMedCrossRefGoogle Scholar
  114. Olefsky, J. M., J. W. Farquhar, and G. M. Reaven. 1974. Reappraisal of the role of insulin in hypertriglyceridemia. Am. J. Med. 57:551–560.PubMedCrossRefGoogle Scholar
  115. Palmer, G. H., and D. G. Dixon. 1968. Effect of pectin dose on serum cholesterol levels. Am. J. Clin. Nutr. 18:437–442.Google Scholar
  116. Patsch, J. R., and A. M. Gotto, Jr. 1980. Role of high density lipoprotein (HDL) in the catabolism of triglyceride-rich lipoproteins. In Lipoprotein and Coronary Heart Disease. M. Greten, P. D. Land, and G. Schettler, eds., pp. 16–24. Baden-Baden, Cologne: G. Witzstock.Google Scholar
  117. Peterson, D. B., P. R. Ellis, J. M. Baylis, P. G. Frost, A. R. Leeds, and A. M. Jepson. 1984. Effects of guar on diabetes and lipids. Food and pharmacology compared. Diabetologia 27:319A.Google Scholar
  118. Quarfordt, S. H., A. Frank, D. M. Shames, M. Berman, and D. Steinberg. 1970. Very low density lipoprotein triglyceride transport in type IV hyperlipoproteinemia and the effects of carbohydrate-rich diets. J. Clin. Invest. 49:2281–2297.PubMedCrossRefGoogle Scholar
  119. Reaven, G. M. 1979. Effects of differences in amount and kind of dietary carbo hydrate on plasma glucose and insulin responses in man. Am. J. Clin. Nutr. 32:2568–2578.PubMedGoogle Scholar
  120. Reaven, G. M., and J. M. Olefsky. 1974. Increased plasma glucose and insulin response to high carbohydrate feeding in normal subjects. J. Clin. Endocr. Metab. 38:151–154.PubMedCrossRefGoogle Scholar
  121. Reiser, S., J. Hallfrisch, O. E. Michaelis, F. L. Lazar, R. E. Martin, and E. S. Prather. 1979. Isocaloric exchange of dietary starch and sucrose in humans. Effects on levels of fasting blood lipids. Am. J. Clin. Nutr. 32:1659–1669.PubMedGoogle Scholar
  122. Rivellese, A., G. Riccardi, A. Giaco, D. Pacioni, S. Gebivesem, P. L. Mattioli, and M. Mancini. 1980. Effect of dietary fibre on glucose control and serum lipoproteins in diabetic patients. Lancet 2:447–450.PubMedCrossRefGoogle Scholar
  123. Roberts, A. M. 1973. Effects of a sucrose-free diet on the serum lipid levels of men of Antarctica. Lancet 1:1201–1204.PubMedCrossRefGoogle Scholar
  124. Rosenthal, M. B., R. J. Barnard, D. P. Rose, S. Inkeles, J. Hall, and N. Pritikin. 1985. Effects of a high-complex-carbohydrate, low-fat, low-cholesterol diet on levels of serum lipids and estradiol. Amer. J. Med. 78:23–27.PubMedCrossRefGoogle Scholar
  125. Ruderman, N. B., A. L. Jones, R. M. Krauss, and E. Shafrir. 1971. A biochemical and morphologic study of very low density lipoproteins in carbohydrate-induced hypertriglyceridemia. J. Clin. Invest. 50:1355–1368.PubMedCrossRefGoogle Scholar
  126. Sandberg, A. T. S., R. Ahderinne, H. Anderson, B. Hallgren, and L. Hutten. 1983. The effect of citrus pectin on the absorption of nutrients in the small intestine. Hum. Nutr. Clin. Nutr. 37:171–184.PubMedGoogle Scholar
  127. Schlierf, G., T. Nikolaus, and A. Stiehel. 1979. The effect of a lipid-lowering diet on biliary and plasma lipids in healthy subjects. Proc. Third Int. Congr. on Biology Value of Olive Oil, I.O.O.C., Crete, pp. 212–220.Google Scholar
  128. Schonfeld, G., S. W. Weidman, J. L. Witztum, and R. M. Bowen. 1976. Alterations in levels and interrelations of plasma apolipoproteins induced by diet. Metabolism 25:261–265.PubMedCrossRefGoogle Scholar
  129. Schwandt, P., W. O. Richter, P. Weiweiler, and G. Neureuther. 1982. Cholestyramine plus pectin in treatment of patients with familial hypercholesterolemia. Atherosclerosis 39:379–383.CrossRefGoogle Scholar
  130. Shepherd, B., C. J. Packard, J. P. Patsch, A. M. Gotto Jr., and O. D. Taunton. 1978. Effects of polyunsaturated fat on the properties of high density lipoproteins and the metabolism of apoprotein A-I. J. Clin. Invest. 61:1582–1592.PubMedCrossRefGoogle Scholar
  131. Sirtori, C. R., E. Agradi, F. Conti, O. Mantero, and E. Gatti. 1977. Soybean-protein diet in the treatment of type-II hyperlipoproteinemia. Lancet 1:275–277.PubMedCrossRefGoogle Scholar
  132. Srinivasan, S. R., B. Radhakrishnamurthy, T. A. Foster, and G. S. Berenson. 1983. Divergent responses of serum lipoproteins to changes in dietary carbohydrate and cholesterol in cynomolgus monkeys. Metabolism 32:377–386.CrossRefGoogle Scholar
  133. Stamler, J. 1979. Population studies. In Nutrition, Lipids and Coronary Heart Disease-A Global View. R. I. Levy, B. M. Rifkind, B. H. Denis, and N. Ernst, eds., pp. 25–31. New York: Raven Press.Google Scholar
  134. Stamler, J., D. Wentworth, and J. Neaton. 1986. Is the relationship between serum cholesterol and risk of death from coronary heart disease continuous and graded? JAMA 256:2823–2828.PubMedCrossRefGoogle Scholar
  135. Stanley, M. M., D. Paul, D. Gacke, and J. Murphy. 1972. Effect of cholestyramine, metamucil and cellulose on fecal bile acid excretion in man. Gastroenterology 65:889–894.Google Scholar
  136. Stasse-Wolthuis, M., H. F. F. Abers, J. G. C. van Jeveren, J. Wil de Jong, J. G. A. J. Hautvast, R. J. J. Hermus, M. B. Katan, W. C. Brydon, and M. A. Eastwood. 1980. Influence of dietary fiber from vegetables and fruits, bran or citrus pectin on serum lipids, fecal lipids and colonic functions. Am. J. Clin. Nutr. 33:1745–1756.PubMedGoogle Scholar
  137. Stone, D. B., and W. E. Connor. 1963. The prolonged effects of a low cholesterol, high carbohydrate diet upon the serum lipids in diabetic patients. Diabetes 12:127–132.PubMedGoogle Scholar
  138. Sturdevant, R. A., M. L. Pearce, and S. Dayton. 1973. Increased prevalence of cholelithiasis in men ingesting a serum-cholesterol-lowering diet. N. Engl. J. Med. 288:24–27.PubMedCrossRefGoogle Scholar
  139. Taskinen, M. R., and E. A. Nikkila. 1981. Lipoprotein lipase of adipose tissue and skeletal muscle in human obesity: response to glucose and to semistarvation. Metabolism 30:810–817.PubMedCrossRefGoogle Scholar
  140. Terpstra, A. H. M., L. Harkes, and F. H. van der Veen. 1981. The effect of different proportions of casein in semipurified diets on the concentration of serum cholesterol and the lipoprotein composition in rabbits. Lipids 16:114–119.PubMedCrossRefGoogle Scholar
  141. Terpstra, A. H. M., R. J. J. Hermus, and C. E. West. 1983. Dietary protein and cholesterol metabolism in rabbits and rats. In Animals and Vegetable Proteins in Lipid Metabolism and Atherosclerosis, pp. 19–49. New York: Alan R. Liss, Inc.Google Scholar
  142. Terpstra, A. H. M., C. E. West, J. T. C. M. Fenis, J. A. Schouten, and E. A. van de Veen. 1984. Hypocholesterolemic effects of dietary soy protein versus casein in rhesus monkey. Am. J. Clin. Nutr. 39:1–7.PubMedGoogle Scholar
  143. Thompson, P. D., R. W. Jeffery, R. R. Wing, and P. D. Wood. 1979. Unexpected decrease in plasma high density lipoprotein cholesterol with weight loss. Am. J. Clin. Nutr. 32:2016–2021.PubMedGoogle Scholar
  144. Thuesen, L., L. B. Henriksen, and B. Engby. 1986. One-year experience with a low-fat, low-cholesterol diet in patients with coronary heart disease. Am. J. Clin. Nutr. 44:212–219.PubMedGoogle Scholar
  145. Tobey, T. A., M. Greenfield, F. Kraemer, and G. M. Reaven. 1981. Relationship between insulin resistance, insulin secretion, very low density lipoprotein kinetics and plasma triglyceride levels in normotriglyceridemic man. Metabolism 30:165–171.PubMedCrossRefGoogle Scholar
  146. Tokunaga, K., K. Ishikawa, and Y. Matsurawa. 1982. Lipids and lipoproteins during a very low caloric diet. Int. J. Obesity 6:416.Google Scholar
  147. Trowell, H. C. 1972. Ischaemic heart disease and dietary fiber. Amer. J. Clin. Nutr. 25:926–932.PubMedGoogle Scholar
  148. Trowell H., and D. Burkitt. 1986. Physiological role of dietary fiber: a ten year review. Contemp. Nutr. 11:1–2.Google Scholar
  149. Trowell, H. C., N. Painter, and D. P. Burkitt. 1974. Aspects of epidemiology of diverticular disease and ischaemic heart disease. Am. J. Dig. Disease 19:864–873.CrossRefGoogle Scholar
  150. Vahouney, G. V. 1982. Dietary fibers and intestinal absorption of lipids. In Dietary Fiber in Health and Disease, G. V. Vahouney and D. Kritchevsky, eds., pp. 203–227. New York and London: Plenum Press.Google Scholar
  151. Van Raaij, J. M. A., M. B. Katan, J. G. A. Hautvast, and R. J. J. Hermus. 1981. Effects of casein versus soy protein diets on serum cholesterol and lipoproteins in young healthy volunteers. Am. J. Clin. Nutr. 34:1261–1271.PubMedGoogle Scholar
  152. Vega, G. L., E. Grozsek, R. Wolf, and S. M. Grundy. 1982. Influence of polyunsaturated fats on composition of plasma lipoproteins and apolipoproteins. J. Lipid Res. 23:811–822.PubMedGoogle Scholar
  153. Verrillo, A., A. De Teresa, P. Giarrusso, and S. La Rocca. 1985. Soybean protein diets in the management of type II hyperlipoproteinemia. Atherosclerosis 54:321–333.PubMedCrossRefGoogle Scholar
  154. Vessby, B., I. B. Gustaffson, J. Boberg, B. Karlstrom, H. Lithell, and I. Werner. 1980. Substituting polyunsaturated for saturated fat as a single change in a Swedish diet: effects on serum lipoprotein metabolism and glucose tolerance in patients with hyperlipoproteinemia. Eur. J. Clin. Invest. 10:193–202.PubMedCrossRefGoogle Scholar
  155. Walker, A. R. P., and U. B. Arvidsson. 1954. Fat intake, serum cholesterol concentration and atherosclerosis in the South African Bantu. J. Clin. Invest. 33:1358–1365.PubMedCrossRefGoogle Scholar
  156. Weinsier, R. L., A. Seeman, G. Herrera, J. P. Assal, J. S. Soeldner, and R. E. Gleason. 1974. High and low-carbohydrate diets in diabetes mellitus. Study of effects on diabetic control, insulin secretion, and blood lipids. Ann. Internal. Med. 80:332–341.Google Scholar

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© Van Nostrand Reinhold 1991

Authors and Affiliations

  • Luciano Cominacini
  • Ulisse Garbin
  • Anna Davoli
  • Beatrice Cenci
  • Ottavio Bosello

There are no affiliations available

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