Advertisement

Terminology and Definitions

  • K. S. Khera
  • H. C. Grice
  • D. J. Clegg
Part of the Current Issues in Toxicology book series (CI TOXICOLOGY)

Abstract

In this chapter terminology and definitions are provided to give precise meaning to the terms that are used in this monograph. The use and meaning of terms employed in teratology studies vary between laboratories (Black and Marks, 1986) and regulatory agencies of different countries. An attempt to achieve worldwide uniformity in the assessment of human risks, particularly those involving prenatal and postnatal development, is an absolute need in view of rising international trade in foods, drugs, chemicals, and other regulated consumer products. Generally accepted terminology and definitions of key terms are necessary prerequisites for achieving such uniformity.

Keywords

Test Substance Postnatal Development Reproductive Toxicity Prenatal Development Human Risk 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Black, D.L. and Marks, T.A. (1986) Inconsistent use of terminology in animal developmental toxicology studies: A discussion. Teratology, 33, 333–338.PubMedCrossRefGoogle Scholar
  2. Clegg, D.J. (1971) Teratology. Annu. Rev. Pharmacol. 11: 409–424.CrossRefGoogle Scholar
  3. Dorland’s Medical Dictionary (1965) 24th ed., pp. 478–547, W.B. Saunders, Philadelphia.Google Scholar
  4. Khera, K.S. (1981) Common fetal aberrations and their teratologic significance: A review. Fund. Appl. Toxicol. 1: 13–18.Google Scholar
  5. WHO (World Health Organization) (1958) Methods for Toxicologic Testing of Food Additives, Technical Report Series, No. 144, pp. 1–19, World Health Organization, Geneva.Google Scholar
  6. WHO (World Health Organization) (1978) Principles and Methods for Evaluating the Toxicity of Chemicals, Part I, Environmental Health Criteria 6, p. 19, World Health Organization, Geneva.Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • K. S. Khera
    • 1
  • H. C. Grice
    • 2
  • D. J. Clegg
    • 1
  1. 1.Health Protection BranchHealth and Welfare CanadaOttawaCanada
  2. 2.NepeanCanada

Personalised recommendations