The Action of Radiation on Enzymes: The Example of Ribonuclease

  • Hermann Dertinger
  • Horst Jung
Part of the Heidelberg Science Library book series (HSL)


The aim of the previous chapters has been to emphasize the basic features as well as the general “laws” of the action of radiation. This forms a sound basis for the understanding of the “biomolecular” portion of this treatise. The study begins with radiation effects on enzymes, although this should not be taken to imply that these phenomena are particularly simple. The structure of enzymes is in some ways much more complicated than that of nucleic acids, and their three-dimensional structure reflects the highly specific catalytic properties. Interest in the action of radiation on enzymes results from the fact that they are essential for the maintenance of vital processes. The aim of this chapter is to derive an approximate picture of the action of radiation on enzymes from the multitude of different observations; but the discussion will be mainly confined to a particularly well-examined enzyme, ribonuclease (RNase), since the quantity and variety of experimental data involved does not allow a collective treatment of the various enzymes.


Electron Spin Resonance Disulphide Bridge Elution Pattern Unirradiated Control Intramolecular Energy Transfer 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1970

Authors and Affiliations

  • Hermann Dertinger
    • 1
  • Horst Jung
    • 1
  1. 1.Nuclear Science CenterUniversity of Heidelberg and Institute for Radiation BiologyKarlsruheGermany

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