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Preparation and Purification of Antibodies to Steroids

  • Ian H. Thorneycroft
  • Stephen A. Tillson
  • Guy E. Abraham
  • Rex J. Scaramuzzi
  • Burton V. Caldwell

Abstract

As discussed in previous papers at this symposium, steroids or other low-molecular-weight compounds are not inherently antigenic (Goodfriend and Sehon, 1970; and Gross, 1970). Landsteiner, however, demonstrated in the early 1900’s that antibodies directed against these low-molecular-weight compounds can be produced if they are chemically conjugated to a substance which is antigenic (see Landsteiner, 1946, for review). When conjugated to the antigen, these low-molecular-weight substances function as haptens.

Keywords

Human Serum Albumin Gamma Globulin Immunologic Method Assay Titer Percent Binding 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1970

Authors and Affiliations

  • Ian H. Thorneycroft
    • 1
  • Stephen A. Tillson
    • 1
  • Guy E. Abraham
    • 1
  • Rex J. Scaramuzzi
    • 1
  • Burton V. Caldwell
    • 1
  1. 1.Worcester Foundation for Experimental BiologyShrewsburyUSA

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