An introduction to intensive design in the evaluation of drug efficacy during psychotherapy

  • J. B. Chassan
  • Leopold Bellak
Part of the The Century Psychology Series book series (TCPS)


The evaluation of psychotropic drugs shares a good many problems with the evaluation of psychotherapy: the problem of valid and reliable judgments, the effect of time, and the problem of understanding and demonstrating the process of the therapeutic effect, rather than a mere evaluation of the result (Bellak, 1961). Not the least among these difficulties derives from the procedure of testing various hypotheses between groups of patients concerning the relative efficacy of two or more medications. The inability to specify particular patient parameters in relation to the statistical results of such studies, the vagueness of the population of patients from which the study patients are presumably considered as a random sample, and the consequent poverty of operational implications of the results of such studies, are among the many difficulties one encounters in what has been called the extensive model of clinical research design.


Active Medication Extensive Model Primary Process Intensive Model Patient Parameter 
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  1. Bellak, L. The use of oral barbiturates in psychotherapy. Amer. J. of Psychiat., 105: 849–850, 1949.Google Scholar
  2. Bellak, L. Research in psychoanalysis. Psa. quart., 30: 519–548, 1961.Google Scholar
  3. Bellak, L., and Smith, M. B. An experimental exploration of the psychoanalytic process. Psa. quart., 25: 385–414, 1956.Google Scholar
  4. Chassan, J. On the unreliability of reliability and some other consequences of the assumption of probabilistic patient-states. Psychiat., 20: 163–171, 1957.Google Scholar
  5. Chassan, J. On the development of clinical statistical systems for psychiatry. Biometrics, 15: 396–404, 1959.CrossRefGoogle Scholar
  6. Chassan, J. Statistical interence and the single case in clinical design. Psychiat., 23:173–184, 1960.Google Scholar
  7. Chassan, J. Stochastic models of the single case as the basis of clinical research design. Behav. Sci., 6: 42–50, 1961.PubMedCrossRefGoogle Scholar
  8. Kellam, S., and Chassan, J.. Social context and symptom fluctuation. Psychiat., 25: 370–381, 1962.Google Scholar

Copyright information

© Meredith Publishing Company 1966

Authors and Affiliations

  • J. B. Chassan
  • Leopold Bellak

There are no affiliations available

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