Cell-Extracellular Matrix Interactions During Primary Mesenchyme Formation in the Sea Urchin Embryo
Gastrulation in different organisms can involve distinct morphogenetic mechanisms, at least at the cellular level. In the sea urchin, two distinct periods of gastrulation are observed (Solursh 1986). One involves the formation of the primary mesenchyme cells, which give rise to the larval skeleton, and the other involves the formation of the archenteron. Each of these illustrate different sorts of cellular activities. The formation of the primary mesenchyme involves an epithelial-mesenchymal transition followed by the apparently random migration of individual mesenchymal cells in the blastocoel until they form two ventral-lateral clumps connected by a ring of cells. The formation of the archenteron involves the infolding of cells at the vegetal plate followed by cellular rearrangements as the archenteron elongates (see chapter by McClay).
KeywordsSulfate Proteoglycan Primitive Streak Sulfate Deprivation Proteoglycan Core Protein Urea Extract
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- Herbst, C. 1904. Über die zur Entwicklung der Seeigelarven nothwendigen anorganischen Stoffe, ihre Rolle und Vertretbarkeit. III. Theil. Die Rolle der nothwendigen anorganischen Stoffe. Wilhelm Rouxs Arch. Dev. Biol. 17:306–520.Google Scholar
- Solursh, M. 1986. Migration of sea urchin primary mesenchyme cells, p. 391–431. In: Developmental Biology: A Comprehensive Synthesis, vol 2, The Cellular Basis of Morphogenesis. L.W. Browder (Ed.). Plenum Press, New York.Google Scholar