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Transcriptional Regulation of c-Ha-ras1 Gene

  • A. Pintzas
  • A. Kotsinas
  • D. A. Spandidos
Part of the NATO ASI Series book series (NSSA, volume 220)

Abstract

Ras genes (H-ras, K-ras and N-ras) appear to be highly conserved throughout the animal kingdom and have been identified in lower eukaryotes (eg yeasts), Dictyostelium, Drosophila and chickens in addition to mammals1. In mammals the ras genes appear to be expressed in all cell types and at all developmental stages. The fact that the genes are highly conserved and constitutively expressed in different cell types has led to the suggestion that they have some essential cellular functions2.

Keywords

Noncoding Exon Distinct Signal Transduction Pathway Multiple Transcription Initiation Site National Hellenic Research Foundation Transcriptional Enhancer Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • A. Pintzas
    • 1
  • A. Kotsinas
    • 2
  • D. A. Spandidos
    • 2
    • 3
  1. 1.Cancer Research Campaign Beatson LaboratoriesThe Beatson Institute for Cancer ResearchBearsden, GlasgowUK
  2. 2.Institute of Biological Research and BiotechnologyNational Hellenic Research FoundationAthensGreece
  3. 3.Medical SchoolUniversity of CreteHeraklionGreece

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