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Molecular Evolution of the Ha-ras-1 Oncogene: Relationship between DNA Methylation, Frequency of CpG Dinucleotides and Binding to the Sp1 Transacting Factor

  • Roberto Gambari
  • Stefano Volinia
  • Giordana Feriotto
  • Rafaella Barbieri
  • Roberta Piva
  • Claudio Nastruzzi
Part of the NATO ASI Series book series (NSSA, volume 220)

Abstract

One of the molecular events involved in the regulation of the expression of cellular oncogenes is the interaction between transcriptional factors and target DNA sequences present in the 5′ genomic portion1.

Keywords

Frequency Ratio Cellular Oncogene Unmethylated State Human Erythroleukemia K562 Cell TAPP Treatment 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Roberto Gambari
    • 1
  • Stefano Volinia
    • 1
  • Giordana Feriotto
    • 1
  • Rafaella Barbieri
    • 1
  • Roberta Piva
    • 1
  • Claudio Nastruzzi
    • 1
  1. 1.Istituto di Chimica BiologicaUniversità di FerraraItaly

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