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Candida Albicans Acid Proteinase: Characterization and Role in Candidiasis

  • Thomas L. Ray
  • Candia D. Payne
  • Brian J. Morrow
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 306)

Abstract

Candida albicans and related species are medically important yeast-like dimorphic fungi that are responsible, in part, for the rising incidence of serious, life-threatening opportunistic infections seen in immunocompromised and debilitated patients. In addition to minor localized infections of cutaneous, oropharyngeal and vaginal epithelium, Candida spp. produce transient or persistent fungemia that leads to systemic infections of virtually any organ (esp. liver, kidney and lung). Hematologic malignancy and transplant patients with prolonged neutropenia and antibiotic resistant fevers are particularly at risk. C. albicans and C. tropicalis are medically the most important, although other species do cause disease, but less frequently.

Keywords

Candida Albicans Candida Species None None Candida Infection Aspartic Proteinase 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Thomas L. Ray
    • 1
  • Candia D. Payne
    • 1
  • Brian J. Morrow
    • 2
  1. 1.The Marshall Dermatology Research Laboratories, Department of DermatologyUniversity of Iowa College of MedicineIowa CityUSA
  2. 2.The Marshall Dermatology Research Laboratories, Department of BiologyUniversity of Iowa College of MedicineIowa CityUSA

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