Biochemical and Biological Characterization of NAP-1/ IL-8-Related Cytokines in Lesional Psoriatic Scale

  • Jens-M. Schröder
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 305)


Psoriasis is a skin disease characterized by epidermal hyperproliferation as well as an inflammatory cell infiltrate in the epidermis predominantly consisting of polymorphonuclear leukocytes (PMN) (1). The absence of bacteria as the cause of PMN infiltration led to the hypothesis that endogenous chemoattractants located in the epidermal cell layer of psoriatic plaques may attract PMN into the inflammatory focus.


Ammonium Formate Psoriatic Lesion Residue Form Neutrophil Chemotactic Factor Exogenous Arachidonic Acid 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Jens-M. Schröder
    • 1
  1. 1.Department of DermatologyUniversity of KielKielWest Germany

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