Abstract
Ca2+ binding to troponin and the resulting thin filament conformational change acts as a switch in striated muscle that enables crossbridges to bind to actin and cycle (Rüegg, 1986). This allosteric “Ca2+-switch” mechanism generates only two primary crossbridge states: free and attached (Huxley, 1957).
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© 1991 Plenum Press, New York
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Hai, CM., Rembold, C.M., Murphy, R.A. (1991). Can Different Four-State Crossbridge Models Explain Latch and the Energetics of Vascular Smooth Muscle?. In: Moreland, R.S. (eds) Regulation of Smooth Muscle Contraction. Advances in Experimental Medicine and Biology, vol 304. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-6003-2_15
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DOI: https://doi.org/10.1007/978-1-4684-6003-2_15
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