A Peptide Antibody that Specifically Inhibits Cathepsin L

  • Clive Dennison
  • Robert N. Pike
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 303)


Cathepsins L is a cysteine proteinase, normally found in lysosomes, but cancer-associated extra-lysosomal variants of cathepsin L, having different molecular weights and pH stability, have been reported and it has been suggested that these may be responsible for the invasive properties of some malignant tumours (Mason et al., 1987; Denhardt et al., 1987; Maciewicz et al, 1989; Rozhin et al., 1989).


Peptide Antibody Mouse Fibroblast Cell Line Human Cathepsin Cysteine Proteinase Cathepsin Amino Acid Sequence Information 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Clive Dennison
    • 1
  • Robert N. Pike
    • 1
  1. 1.Department of BiochemistryUniversity of NatalPietermaritzburgSouth Africa

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