Strategies for Type-Specific Glycoconjugate Vaccines of Streptococcus pneumoniae
Prevention of bacterial infections in infants by Grampositive and Gram-negative encapsulated microrganisms is still a world-wide concern. According to reliable estimates (US National Institute of Allergy and Infectious Diseases, 1986) the infant mortality by Streptococcus pneumoniae approaches to seven million cases annually and the mortality by encapsulated bacteria (Streptococcus pneumoniae, Haemophilus influenzae type B and Neisseria meningitidis) accounts for about 38% of the total burden by infectious diseases.
KeywordsStreptococcus Pneumoniae Pneumococcal Vaccine Capsular Polysaccharide Diphtheria Toxin Polysaccharide Vaccine
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