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Introduction: Is There a Boundary between Promotion and Progression?

  • Oscar Sudilovsky
Part of the Basic Life Sciences book series (BLSC, volume 57)

Abstract

The need for a meeting that would discuss the poorly defined areas of promotion and progression, and the impetus to promote it, came as a result of a Gordon Conference on Cancer in August, 1987. It had become evident to me and other participants that the concepts of promotion and progression as two separate stages in a multi-step model of carcinogenesis required further evaluation.

Keywords

Visible Tumor Separate Stage Promotion Stage Euploid Cell Initiation Initiate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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    L. Foulds, Mammary tumors in hybrid mice: growth and progression of spontaneous tumors, Brit J Cancer 3:345–375 (1949).PubMedCrossRefGoogle Scholar
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    Y. S. Fu, J. W. Reagan, and R. M. Richart, Definition of precursors. Gynecol Oncol 12:S220–S231 (1981).PubMedCrossRefGoogle Scholar
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    O. Sudilovsky, T. K. Hei, Aneuploid nuclear DNA content in some enzyme-altered rat liver foci during tumor promotion. Fed Proc 42:2225 (1983).Google Scholar
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    H. C. Pitot, “Fundamentals of Oncology,” 3rd edition, p. 190, Marcel Dekker, Inc., New York (1986).Google Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Oscar Sudilovsky
    • 1
  1. 1.School of MedicineCase Western Reserve UniversityClevelandUSA

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