A New Monoclonal Antibody to an Age Sensitive Band 3 Transmembrane Segment
The appearance of band 3 structural modifications related to aging could be evidenced by means of monoclonal antibodies against senescence antigen. Hence in the attempt to provide an immunological marker of erythrocyte aging, we raised a monoclonal antibody against native band 3 (B6 MoAb), which seems to detect differences in the band 3 molecule from erythrocytes of different ages separated by density gradient.
KeywordsHuman Erythrocyte Membrane Membrane Ghost Senescence Antigen Erythrocyte Band Immunoblotting Pattern
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