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A New Monoclonal Antibody to an Age Sensitive Band 3 Transmembrane Segment

  • Lucietta Ferroni
  • Anna Giuliani
  • Stefano Marini
  • Patrizia Caprari
  • Anna Maria Salvati
  • Saverio C. Condò
  • Maria Teresa Ramacci
  • Bruno Giardina
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 307)

Summary

The appearance of band 3 structural modifications related to aging could be evidenced by means of monoclonal antibodies against senescence antigen. Hence in the attempt to provide an immunological marker of erythrocyte aging, we raised a monoclonal antibody against native band 3 (B6 MoAb), which seems to detect differences in the band 3 molecule from erythrocytes of different ages separated by density gradient.

Keywords

Human Erythrocyte Membrane Membrane Ghost Senescence Antigen Erythrocyte Band Immunoblotting Pattern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Lucietta Ferroni
    • 1
  • Anna Giuliani
    • 1
  • Stefano Marini
    • 2
  • Patrizia Caprari
    • 1
  • Anna Maria Salvati
    • 1
  • Saverio C. Condò
    • 2
  • Maria Teresa Ramacci
    • 3
  • Bruno Giardina
    • 2
  1. 1.Istituto Superiore di SanitàRomaItaly
  2. 2.II Università di RomaRomaItaly
  3. 3.Sigma Tau, PomeziaRomaItaly

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