Bacterial Glycosidases and Degradation of Glycoconjugates in the Human Gut

  • Lansing C. Hoskins
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 58)


When examining the molecular pathogenesis of gastrointestinal infections investigators should realize that colon contents contain a variety of hydrolases including proteases, phospholipases, and glycosidases. Their action on cell surface and surface-related structures in the intestine presumably influence both normal and pathological host-microbial associations. This is especially true of intralumenal glycosidases, since oligosaccharide moieties of cell membrane glycolipids and glycoproteins appear to have roles as molecular recognition sites for bacterial attachment (1) while those of mucin glycoproteins confer the viscoelastic gel properties to the overlying mucus layer (I. Carlstedt, this symposium) which is a habitat for some kinds of enteric bacteria (2).


Blood Group Enteric Bacterium Oligosaccharide Chain Fecal Culture Fecal Extract 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations used in text




















hog gastric mucin


N-Acetylneuraminic (sialic acid)


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Lansing C. Hoskins
    • 1
    • 2
  1. 1.Veterans Affairs Medical CenterClevelandUSA
  2. 2.Case Western Reserve University School of MedicineClevelandUSA

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