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The Role of Large Intestine Mucus in Colonization of the Mouse Large Intestine by Escherichia Coli F-18 and Salmonella Typhimurium

  • Paul S. Cohen
  • Beth A. McCormick
  • David P. Franklin
  • Robert L. Burghoff
  • David C. Laux
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 58)

Abstract

Little information is available as to the role of mucus in bacterial colonization of the intestinal tract. We are interested in defining that role.

Keywords

Large Intestine Mucus Layer Intestinal Mucus Public Health Service Grant Good Colonizer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Cohen, P.S., Rossell, R., Cabelli, V.J., Yang, S.L., and Laux, D.C. Relationship between the mouse colonizing ability of a human fecal Escherichia coli strain and its ability to bind a specific mouse colonic mucous gel protein. Infect. Immun. 40:62–69, 1983.PubMedGoogle Scholar
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    McCormick, B.A., Stocker, B.A.D., Laux, D.C., and Cohen, P.S. Roles of motility, chemotaxis, and penetration through and growth in intestinal mucus in the ability of an avirulent strain of Salmonella tvphimurium to colonize the large intestine of streptomycin-treated mice Infect. Immun. 56:2209–2217, 1988.Google Scholar
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    Wadolkowski, E.A., Laux, D.C., and Cohen, P.S. Colonization of the streptomycin-treated mouse large intestine by a human fecal Escherichia coli strain: role of growth in mucus. Infect. Immun. 56:1030–1035, 1988.PubMedGoogle Scholar
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    Franklin, D.P., Laux, D.C., Williams, T.J., Falk, M.C., and Cohen, P.S. Growth of Salmonella tvphimurium SL5319 and Escherichia coli F-18 in mouse cecal mucus: role of peptides and iron. FEMS Microbiol. Ecol. (in press).Google Scholar
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    McCormick, B.A., Franklin, D.P., Laux, D.C., and Cohen, P.S. Type 1 pili are not necessary for colonization of the streptomycin-treated mouse large intestine by type 1-piliated Eschericha coli F-18 and E. coli K-12. Infect. Immun. 57:3022–3029, 1989.PubMedGoogle Scholar
  6. 6.
    McCormick, B.A., Laux, D.C., and Cohen, P.S. Neither motility nor chemotaxis play a role in the ability of Escherichia coli F-18 to colonize the streptomycin-treated mouse large intestine. Infect. Immun. 58:2957–2961, 1990.PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Paul S. Cohen
    • 1
  • Beth A. McCormick
    • 1
  • David P. Franklin
    • 1
  • Robert L. Burghoff
    • 1
  • David C. Laux
    • 1
  1. 1.Department of MicrobiologyUniversity of Rhode IslandKingstonUSA

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