The Enterocyte and its Brush Border

  • Robert W. Lobley
Part of the Federation of European Microbiological Societies Symposium Series book series (FEMS, volume 58)


The close relationship between physical structure and physiological function is nowhere more apparent than in the small intestine. The mucosal surface is lined with a virtually continuous epithelial monolayer of columnar enterocytes that constitute the primary cellular barrier between the intestinal lumen and the internal milieu. These cells are therefore a prime target for microbial attack during infections of the gut, and many aspects of the pathogenesis of gastrointestinal infections can be properly understood only in the context of molecular interactions between the micro-organism and the enterocyte.


Brush Border Brush Border Membrane Paracellular Permeability Intestinal Brush Border Microvillus Membrane 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Robert W. Lobley
    • 1
  1. 1.Department of GastroenterologyRoyal InfirmaryManchesterUK

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