Regulation of Thyroid Function in Pregnancy: Maternal and Neonatal Repercussions
Pregnancy constitutes a unique experimental model in humans, wherein a normal thyroid is faced with a triple challenge, as a result of 3 separate factors acting in concert to stimulate the gland: 1) the increased thyroid hormone-binding capacity of serum, 2) the effects of increased levels of hCG on TSH and on the thyroid, and 3) the reduced availability of iodine for the maternal thyroid, at least in conditions with a limited dietary iodine supply.
KeywordsIodine Intake Thyroid Volume Maternal Thyroid Iodine Supply Neonatal Thyroid
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