Regulation of Thyroid Function in Pregnancy: Maternal and Neonatal Repercussions

  • Daniel Glinoer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 299)


Pregnancy constitutes a unique experimental model in humans, wherein a normal thyroid is faced with a triple challenge, as a result of 3 separate factors acting in concert to stimulate the gland: 1) the increased thyroid hormone-binding capacity of serum, 2) the effects of increased levels of hCG on TSH and on the thyroid, and 3) the reduced availability of iodine for the maternal thyroid, at least in conditions with a limited dietary iodine supply.


Iodine Intake Thyroid Volume Maternal Thyroid Iodine Supply Neonatal Thyroid 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Daniel Glinoer
    • 1
  1. 1.Laboratory of Radioisotopes Thyroid Investigation Clinic Hospital Saint-PierreFree University of BrusselsBrusselsBelgium

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