Effects of Tryptophan on the Development of Deoxycorticosterone Acetate (DOCA)-Induced Hypertension in Rats
For some years, we have been interested in the role of neutral amino acids in the development and maintenance of hypertension. Our initial studies with tyrosine suggested that chronic dietary treatment with this essential amino acid could provide modest protection against the development of renal hypertension in rats (Lockley et al., 1985). However, it was considerably less effective in protecting against the development of deoxycorticosterone (DOCA)-induced hypertension (Henley et al., 1986).
KeywordsChronic Treatment Antihypertensive Effect Isotonic Saline Neutral Amino Acid Heart Weight
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