Inhibition of Tryptophan → Niacin Metabolism by Dietary Leucine and by Leucine and 2-Oxo-isocaproate in vitro
A relative excess of leucine in dietary proteins has been implicated in the etiology of the tryptophan-niacin deficiency disease pellagra in those parts of India where the dietary staple is jowar (Sorghum vulgare) (Gopalan and Srikantia, 1960).
KeywordsXanthurenic Acid Relative Excess Dietary Staple Sorghum Vulgare Tryptophan Diet
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