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Melatonin Receptors in the Central Nervous System

  • M. L. Dubocovich
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 294)

Abstract

The hormone melatonin is synthesized primarily in the pineal gland of vertebrates from its precursor serotonin (5-hydroxytryptamine). Serotonin is N-acetylated by a relatively specific N-acetyltransferase to yield N-acetylserotonin, which in turn is methylated by hydroxyindole-O-methyltransferase to melatonin (5-methoxy-N-acetyltryptamine) (Axelrod, 1974).

Keywords

Pineal Gland Dopamine Release Syrian Hamster Median Eminence Suprachiasmatic Nucleus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • M. L. Dubocovich
    • 1
  1. 1.Department of PharmacologyNorthwestern University Medical SchoolChicagoUSA

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