Glucose Transporters in Central Nervous System Glucose Homeostasis

  • Bartosz Z. Rydzewski
  • Magdalena M. Wozniak
  • Mohan K. Raizada
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 293)


The brain is considered to be a glucose-obligatory organ, that is neuronal and glial cells from the central nervous system (CNS) are dependent on glucose as a sole energy source1. The ability of various anatomical areas of the brain to utilize glucose has been shown to have a major impact on the control of certain physiological and behavioral functions of the brain. This has resulted in an increased desire to elucidate the cellular and molecular mechanisms involved in the transport, metabolism, and sensitivity to the glucose in the brain. Recent identification and characterization of a facilitative glucose transporter family have set a pace for research involving glucose uptake systems present in the brain cells.


Glucose Transporter Glut1 Expression Glut1 mRNA Facilitative Glucose Transporter Astroglial Culture 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Bartosz Z. Rydzewski
    • 1
  • Magdalena M. Wozniak
    • 2
  • Mohan K. Raizada
    • 1
  1. 1.Department of Physiology (B.Z.R., M.K.R), College of MedicineUniversity of FloridaGainesvilleUSA
  2. 2.Department of Pharmacology & Experimental Therapeutics (M.M.W.), College of MedicineUniversity of FloridaGainesvilleUSA

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