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Molecular Heterogeneity of Insulin Receptors in Rat Tissues

  • Barry J. Goldstein
  • Alana L. Dudley
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 293)

Abstract

Heterogeneity in the structure and function of the insulin receptor in various tissues and animal species has recently been reported by several laboratories. Our laboratory has been interested in determining the molecular basis for this variation in the insulin receptor, which may be involved in the regulation of certain actions of insulin in target cells. This brief presentation will summarize our recent work in this area which has used a variety of molecular approaches to study the structure of the coding region of insulin receptor mRNA transcripts in several rat tissues.

Keywords

Insulin Receptor Insulin Receptor Gene Human Insulin Receptor Insulin Receptor mRNA Brain Insulin Receptor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Barry J. Goldstein
    • 1
    • 2
  • Alana L. Dudley
    • 1
    • 2
  1. 1.Research DivisionJoslin Diabetes CenterBostonUSA
  2. 2.Department of Medicine, Brigham Women’s HospitalHarvard Medical SchoolBostonUSA

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