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DNA Technology for Prenatal Diagnosis of Cystic Fibrosis in Italy

  • M. Seia
  • G. Cozzi
  • L. Sereni
  • M. Ferrari
  • L. Cremonesi
  • A. E. Covone
  • L. Fenu
  • P. Ronchetto
  • M. Devoto
  • G. Romeo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 290)

Abstract

Since 1985, genetic diagnosis of Cystic Fibrosis (CF) by RFLPs analysis (Tsui L.-C. et al., 1985; Wainwright et al., 1985) is available in families with affected children.

Keywords

Cystic Fibrosis Prenatal Diagnosis Cystic Fibrosis Patient Genetic Diagnosis Affected Child 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Tsui, L.-C., Buchwald, M., Barker, D., Braman, J.C., Knowlton, R., Schumm, J.W., Eiberg. H., Mohr, J., Kennedy, D., Plavsic, N., Zsiga, M., Markiewicz, D., Akots, G., Brown, V., Helms, C., Gravius, T., Parker, C., Rediker, K., Donis Keller, H., 1985, Cystic Fibrosis locus to human chromosome 7cen-q22, Nature, 318:384.Google Scholar
  2. Wainwright, B.J., Scambler, P.J., Schmidtke, J., Watson, E.K., Law, H.-Y., Farral, M., Cooke, H.J., Eiberg, H., Williamson, R., 1985, Localization of cystic fibrosis locus to human chromosome 7cen-q22, Nature, 318:384.PubMedCrossRefGoogle Scholar
  3. Kerem, B., Rommens, J.M., Buchanan, J., Marchiewicz, D., Cox, T.K., Chakravarti, A., Buchwald, M., Tsui, L.-C., 1989b, Identification of the cystic fibrosis gene: genetic analysis, Science, 245:1073.PubMedCrossRefGoogle Scholar
  4. Riordan, J.R., Rommens, J.M., Kerem, B., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J.-L., Drumm, M.L., Iannuzzi, M.C., Collins, F.S., Tsui, L.C., 1989, Identification of the Cystic Fibrosis gene: cloning and characterization of complementary DNA, Scienze, 245:1066.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • M. Seia
    • 1
  • G. Cozzi
    • 1
  • L. Sereni
    • 1
  • M. Ferrari
    • 2
  • L. Cremonesi
    • 2
  • A. E. Covone
    • 3
  • L. Fenu
    • 3
  • P. Ronchetto
    • 3
  • M. Devoto
    • 3
  • G. Romeo
    • 3
  1. 1.Lab. Ricerche ClinicheICPMilanItaly
  2. 2.Ist. Scient.Ospedale San Raffaele Lab. CentraleMilanItaly
  3. 3.Lab. Genetica MolecolareIstituto G.GasliniGenoaItaly

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