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Human Placental Membrane Vesicles as Models for Investigation of Cystic Fibrosis

  • A. K. Keenan
  • M. Cregg
  • D. Faller
  • C. Doolan
  • C. Somers
  • M. X. Fitzgerald
  • M. P. Ryan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 290)

Abstract

The human placenta is a rich source of epithelial material with high transport capabilities containing the same genotype as the foetus. The CF gene is expressed in placenta which constitutes an available source of human biopsy material suitable for investigation of transport defects in CF.The human placenta is a rich source of epithelial material with high transport capabilities containing the same genotype as the foetus. The CF gene is expressed in placenta which constitutes an available source of human biopsy material suitable for investigation of transport defects in CF.

Keywords

Cystic Fibrosis Human Placenta Chloride Transport Transport Defect Basolateral Membrane Vesicle 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Reference

  1. Whitsett, J., Johnson, C.L., Noguchi, A., Darovec-Beckerman, C. & Costello, M. (1980) J. Clin. Endocrinol. and Metabolism 50, 27.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • A. K. Keenan
    • 1
  • M. Cregg
    • 1
  • D. Faller
    • 1
  • C. Doolan
    • 1
  • C. Somers
    • 1
  • M. X. Fitzgerald
    • 1
  • M. P. Ryan
    • 1
  1. 1.Departments of Pharmacology and MedicineUniversity CollegeBelfield, Dublin 4Ireland

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