Prevalence of the Major Mutation of the CF Gene in Belgian Patients

  • P. Cochaux
  • R. Van Geffel
  • D. Baran
  • G. Vassart
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 290)


We had previously examined the KM19-XV2C 2–1 haplotype frequency in a sample of Belgian cystic fibrosis patients (ref.l). The results obtained were similar to those published by Beaudet et al (ref.2) : this haplotype was present in 89% of the CF chromosomes.


Cystic Fibrosis Clinical Diagnosis Index Case Haplotype Frequency Genetic Diagnosis 
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  1. 1.
    Devoto et al., 1989, Genomics, 5:894–898.PubMedCrossRefGoogle Scholar
  2. 2.
    Beaudet et al., 1988, The New Eng. J. of Med., 318–1:50–51.Google Scholar
  3. 3.
    Kerem et al., 1989, Science, 245:1073–1080.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • P. Cochaux
    • 1
  • R. Van Geffel
    • 3
  • D. Baran
    • 2
  • G. Vassart
    • 1
  1. 1.Service de GenetiqueHopital Erasme (Bat.C)BrusselsBelgium
  2. 2.Service de PneumologieHopital Erasme (Bat.C)BrusselsBelgium
  3. 3.Service de PediatrieHopital de Braine L’AlleudBraine L’AlleudBelgium

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