Purification of the Epithelial Cl Channel
Chloride channels are present in plasma membranes and in intracellular organelles. In a variety of epithelial cells these channels mediate NaCl absorption and secretion. The aim of our work was to purify the Cl channel and to develop molecular reagents that could be used to study the biochemical basis of cystic fibrosis.
KeywordsCystic Fibrosis Chloride Channel Parafollicular Cell Soybean Phospholipid Cetic Acid
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