Pros and Cons of Neonatal Screening for Cystic Fibrosis
In the past, several experimental schemes for neonatal screening for the presence of Cystic Fibrosis have been tried out. Several benefits of early detection have been claimed, but few studies are methodologically flawless, mainly because of the use of historical controls and/or a too short period of follow-up. At least initially, many programs suffered from the fact that after detection no systematic patient treatment scheme was available, and that no consensus was available on optimal treatment. The life expectancy of patients with cystic fibrosis has considerably improved over the last decades, mainly because better antibiotics became available and because treatment of complications has improved.
KeywordsCystic Fibrosis Prenatal Diagnosis Carrier Status Assortive Mating Neonatal Screening
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