Pros and Cons of Neonatal Screening for Cystic Fibrosis

  • Gerard J. te Meerman
  • Jeannette E. Dankert-Roelse
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 290)


In the past, several experimental schemes for neonatal screening for the presence of Cystic Fibrosis have been tried out. Several benefits of early detection have been claimed, but few studies are methodologically flawless, mainly because of the use of historical controls and/or a too short period of follow-up. At least initially, many programs suffered from the fact that after detection no systematic patient treatment scheme was available, and that no consensus was available on optimal treatment. The life expectancy of patients with cystic fibrosis has considerably improved over the last decades, mainly because better antibiotics became available and because treatment of complications has improved.


Cystic Fibrosis Prenatal Diagnosis Carrier Status Assortive Mating Neonatal Screening 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • Gerard J. te Meerman
    • 1
  • Jeannette E. Dankert-Roelse
    • 2
  1. 1.Department of Medical GeneticsUniversity of GroningenGroningenThe Netherlands
  2. 2.Department of PediatricsFree University of AmsterdamAmsterdamThe Netherlands

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