Relationships Between the Hypothalamus and Adipose Tissue Mass
A system influencing the availability of energy to the entire organism, expectedly, depends on a widespread network directed by the central nervous system. Indeed, there are complex interactions between “controllers” in the brain and peripheral mechanisms for energy consumption and release, as well as the complex machinery mediating chemical energy storage (predominantly as triglyceride) and mobilization. Critical afferent and efferent systems connect the hypothalamic and other brain centres which control food intake and energy disposal, with the relevant target sites. This brief review will summarize four mechanisms whereby the brain, particularly the hypothalamus along with its interconnecting neural structures, can influence body fat content.
KeywordsParaventricular Nucleus Increase Food Intake Decrease Food Intake Ventromedial Nucleus Acidic Fibroblast Growth Factor
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