Hypoglycemia, Gluconeogenesis and the Brain

  • A. D. Cherrington
  • R. T. Frizzell
  • D. W. Biggers
  • C. C. Connolly
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 291)


The purpose of this chapter is to review the role which gluconeo- genesis plays in the response to insulin-induced hypoglycemia and to assess the influence of the brain in driving that response. The chapter is divided into three parts: the response of gluconeogenesis to hypoglycemia; the role of the brain in driving hormone secretion, and as a result gluconeogenesis, during hypoglycemia; and the role of the brain in stimulating gluconeogenesis directly during glucodeprivation.


Vertebral Artery Glucose Production Insulin Infusion Counterregulatory Hormone Autoregulatory Response 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • A. D. Cherrington
    • 1
  • R. T. Frizzell
    • 1
  • D. W. Biggers
    • 1
  • C. C. Connolly
    • 1
  1. 1.Department of Molecular Physiology and BiophysicsVanderbilt University Medical SchoolNashvilleUSA

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