Role of the TAR Element in Regulating HIV Gene Expression

  • Richard Gaynor
Part of the GWUMC Department of Biochemistry Annual Spring Symposia book series (GWUN)


The human immunodeficiency virus long terminal repeat (HIV LTR) is regulated by multiple cis-acting regulatory sequences.1 Cellular factors which bind to the enhancer, SP1, TATA, and TAR regions are involved in the transcriptional regulation of HIV.2 In addition to cellular proteins, the viral protein, tat, has been shown to greatly stimulate HIV gene expression from the HIV LTR.3, 4


Human Immunodeficiency Virus Human Immunodeficiency Virus Type Loop Sequence Stem Structure HeLa Nuclear Extract 


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Richard Gaynor
    • 1
  1. 1.Division of Hematology-OncologyUCLA School of MedicineLos AngelesUSA

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