Rous Sarcoma Virus Gag Gene Sequences Affect Viral RNA Splicing and Stability
A feature common to the life cycles of all retroviruses is the incomplete splicing of the primary viral RNA transcript. While splicing of a subset of the primary transcripts is necessary to generate subgenomic mRNAs (including env mRNA and additional mRNAs in the more complex retroviruses), a major fraction of the RNA transcripts are transported to the cytoplasm in an unspliced form, where they serve both as mRNA and as genomic RNA (Coffin, 1990; Stoltzfus, 1989).
KeywordsSplice Acceptor Site Triosephosphate Isomerase Rous Sarcoma Virus Nonsense Codon Field Virology
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