Opiates, Human Peripheral Blood Mononuclear Cells, and HIV

  • Phillip K. Peterson
  • Burt M. Sharp
  • Genya Gekker
  • Brooks Jackson
  • Henry H. BalfourJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 288)


Remarkably, interest in the pathogenetic effect of opiates on the course of bacterial infection can be traced to the late 19th century (1). Although the infectious disease complications of intravenous (IV) drug use were clearly recognized by the mid-20th century (2,3), serious attention to the mechanisms whereby opiates might participate in the pathogenesis of infectious disease did not surface until the past decade. Contemporary interest in this area of research has been rekindled, in no small way, by the epidemic of acquired immunodeficiency syndrome (AIDS) and realization that IV drug users are a critically important high risk group in the spread of this devastating infection (4).


Human Immunodeficiency Virus Type Drug User Normal Donor Human Peripheral Blood Mononuclear Cell Phorbol Myristate Acetate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Phillip K. Peterson
    • 1
    • 2
    • 3
  • Burt M. Sharp
    • 1
    • 2
    • 3
  • Genya Gekker
    • 1
    • 2
    • 3
  • Brooks Jackson
    • 1
    • 2
    • 3
  • Henry H. BalfourJr.
    • 1
    • 2
    • 3
  1. 1.Department of MedicineHennepin County Medical CenterMinneapolisUSA
  2. 2.Department of Laboratory Medicine and PathologyUniversity of Minnesota HospitalsMinneapolisUSA
  3. 3.University of Minnesota Medical SchoolMinneapolisUSA

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