Effects of Cocaine and Other Drugs of Abuse on Immune Function
Approximately 19 years ago, Falek et al. (1) reported that heroin addicts frequently exhibit abnormally high levels of cytogenetic damage in their T-lymphocytes after mitogenic stimulation in vitro with the plant lectin, phytohemag-glutinin. Later, Madden et al. (2) showed that this damage was probably due to altered DNA-repair capacity of lymphocytes. Less obvious, perhaps, than the genetic implications of these findings were their immunological implications, which, in fact, were significant.
KeywordsHepatitis Depression Morphine Cocaine Alkaloid
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