Effect of Delta-9-Tetrahydrocannabinol on Mitogenic and Antigenic Stimulation of Lymphoid Cells from Inbred Hamsters Infected with Treponema Pallidum Subsp. Pallidum

  • Lois J. Paradise
  • Angela Pruitt
  • Andrew W. O’B. Burgess
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 288)


The currently increased incidence of syphilis appears to be associated with drug abuse in adults and, when congenital syphilis occurs, with a lack of prenatal care in drug-abusing, pregnant women. Advances in understanding of the immune response to Treponema pallidum subsp. pallidum (T. pallidum hereafter), the etiologic agent of syphilis, and in identification of protective, treponemal immunogens suggest that a vaccine may become available for prevention of syphilis. Therefore, it would be of value to know whether the population at highest risk is capable of responding immunologically to T. pallidum.


Stimulation Index Marijuana Smoker Congenital Syphilis Murine Spleen Body Surface Temperature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Lois J. Paradise
    • 1
  • Angela Pruitt
    • 1
  • Andrew W. O’B. Burgess
    • 1
  1. 1.Department of Medical Microbiology and ImmunologyUniversity of South Florida College of MedicineTampaUSA

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